High-throughput determination of adsorption equilibria for chromatographic oligosaccharide separations

Chilamkurthi, Sreekanth; Willemsen, Jan-Hein; Wielen, Luuk A.M. van der; Poiesz, Edwin; Ottens, Marcel

doi:10.1016/j.chroma.2012.03.042

Cited by 25 publications

(13 citation statements)

References 46 publications

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“…The eluent then breaks these interactions and desorbs them in order of decreasing molar mass. Even sugars of the same molar mass (such as glucose and mannose) were separated using this method as the separation also depended on ion exclusion, steric exclusion, electrostatic attraction or repulsion and van der Waals forces among others . The most commonly used column is based on calcium cation, as it was eluted with water alone which prevented the use of co‐solvent that made oligomers of higher DP precipitate .…”

Section: Cellulose Oligomer Separation At Preparative Scalementioning

confidence: 99%

Water-soluble cellulose oligomer production by chemical and enzymatic synthesis: a mini-review

et al. 2017

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This mini‐review focuses on the production of water‐soluble cellulose oligomers. They are easier to handle than cellulose while still having some very interesting cellulose features. Their production is not trivial and they are thus seldom commercially available or are available at high prices and only in small quantities (100 mg or less). The goal of this mini‐review is to describe various routes to obtain these cellulose oligomers. Several examples of chemical or enzymatic synthesis and enzymatic or acidic depolymerization are presented. All the pathways considered are then compared according to several criteria: polymerization degree, yield, availability and cost of reagents, reaction time, etc. As most of the pathways produce a mixture of cellulose oligomers, techniques to separate them according to their length are also discussed. © 2017 Society of Chemical Industry

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Section: Cellulose Oligomer Separation At Preparative Scalementioning

confidence: 99%

Water-soluble cellulose oligomer production by chemical and enzymatic synthesis: a mini-review

et al. 2017

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“…whole chromatographic separation process [8]. Adsorption isotherms are considered like "working curves" whose knowledge is required to maximize the yield of product purification [9].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Adsorption equilibrium of citric acid from supercritical carbon dioxide/ethanol on cyano column

Lü

GuoqingWang

Zhang

et al. 2015

Chinese Journal of Chemical Engineering

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“…The linear isotherm model and the Langmuir isotherm model generally used for the adsorption of a solute in liquid solution , were tested to determine the best fit of the experimental data. The mathematical models are expressed in Eqs.…”

Section: Modeling Of the Separation Process In A Chromatographic Columnmentioning

confidence: 99%

Competitive effect of glucose–fructose adsorption in a fixed‐bed chromatographic column

Tangpromphan

Kaewchada

Jaree

2016

J of Separation Science

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A continuous separation system such as a simulated moving-bed process requires adsorption data with precise equilibrium and kinetic model parameters of a single chromatographic column. The adsorption of glucose and fructose in a fixed-bed chromatographic column was investigated to determine the competition effect of each component resulting from their initial molar ratios. The model parameters including bed porosity and axial dispersion coefficient were determined using the moment analysis method. The equilibrium isotherm parameters were estimated by conducting experiments at various molar ratios and initial sugar concentrations. The parameters obtained were then used for the simulation of dynamic breakthrough curves of glucose and fructose. The equilibrium isotherms revealed that the linear adsorption pattern provided good prediction for each molar ratio using the Henry equation. In addition, the modified Langmuir model was proposed to account for the competitive adsorption, due to the cooperative competition effect whereby glucose was promoted to the active sites by fructose to a greater degree than vice versa. A good agreement between the experimental and numerical data of the adsorption time profiles was also observed.

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High-throughput determination of adsorption equilibria for chromatographic oligosaccharide separations

Cited by 25 publications

References 46 publications

Water-soluble cellulose oligomer production by chemical and enzymatic synthesis: a mini-review

Water-soluble cellulose oligomer production by chemical and enzymatic synthesis: a mini-review

Adsorption equilibrium of citric acid from supercritical carbon dioxide/ethanol on cyano column

Competitive effect of glucose–fructose adsorption in a fixed‐bed chromatographic column

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