High-throughput quantification of eighteen heterocyclic aromatic amines in roasted and pan-fried meat on the basis of high performance liquid chromatography-quadrupole-orbitrap high resolution mass spectrometry

Xu, Yan; Li, Haixia; Liang, Jian; Ma, Jina; Yang, Juan; Zhao, Xiaojuan; Zhao, Wei; Bai, Weidong; Zeng, Xiaofang; Dong, Hao

doi:10.1016/j.foodchem.2021.130147

Cited by 70 publications

(23 citation statements)

References 40 publications

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“…After optimizing the conditions of chromatog-raphy and mass spectrometry, the extracted ion chromatograms and MS/MS spectra of the three BPs (200 μg/L) were shown in Figures 3B and 3C, respectively. Moreover, in order to verify the analytical performance of the developed method, some characteristic parameters, including linearity (linear range, correlation coefficients), LODs, LOQs, accuracy (recovery), precision (n = 6), and enrichment factor (EF) were investigated according to previous literature [21][22][23][24]. A series of mixed standard solutions (mass concentration: 1, 2, 5, 10, 20, 50, 100, 200 μg/L) were prepared using initial mobile phase (MeOH/0.05% ammonia, 40/60%).…”

Section: Methods Validationmentioning

confidence: 99%

Biomass magnetic porous carbon prepared from mangosteen shell for the preconcentration of three bisphenols from beverages followed by liquid chromatography with quadrupole‐Orbitrap high‐resolution mass spectrometry determination

Deng

Wang

et al. 2022

J of Separation Science

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Natural biomass magnetic porous carbon was successfully prepared via a costeffective and green route using mangosteen shells as raw material. The prepared magnetic porous carbon was used as a magnetic solid-phase extraction adsorbent for bisphenols enrichment from beverages followed by high-performance liquid chromatography-quadrupole-Orbitrap high-resolution mass spectrometry. Parameters affecting extraction efficiency including sample solution pH, adsorbent amount, extraction time, eluent type, and volume were optimized. Results showed that biomass magnetic porous carbon had excellent adsorption properties for bisphenols due to its large specific surface area and abundant functional groups, which could form hydrogen bonding and π-π stacking with bisphenols. The enrichment factor of 3 bisphenols was in the range of 15-19. Under optimum conditions, favorable linearity for all analytes was obtained with correlation coefficients higher than 0.998. Recoveries of spiked samples were in the range of 88.5-105.1% with a relative standard deviation of 3.4-5.5%. These results demonstrated that magnetic porous carbon may be a promising adsorbent for the enrichment of aromatic compounds.

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Section: Methods Validationmentioning

confidence: 99%

Biomass magnetic porous carbon prepared from mangosteen shell for the preconcentration of three bisphenols from beverages followed by liquid chromatography with quadrupole‐Orbitrap high‐resolution mass spectrometry determination

Deng

Wang

et al. 2022

J of Separation Science

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“…To estimate the MEs, two modified SPs stock solutions were diluted to five levels with or without 10 μg/L modified SIL peptides by the tryptic hydrolysates of rice and food product. MEs were calculated from the ratio of the slope of matrix‐matched standard curves and solvent‐based standards using the following formula: matrix effects (%) = (B/A − 1) × 100 (Chen et al, 2019; Huang et al, 2020; Xu et al, 2021), where B is the slope of the matrix‐matched calibration curve and A is the slope from spiked pure solvent (80% ACN aqueous solution containing 0.1% FA). The MEs were considered significant signal suppression or enhancement caused by matrix interference when ratio values differed by >20% (Sun et al, 2019; Xu et al, 2021).…”

Section: Methodsmentioning

confidence: 99%

Quantification of rice α‐globulin allergen using liquid chromatography–tandem mass spectrometry combined with cysteine‐specific modifier and extended stable isotope‐labeled peptide

Yang

Cao

Mou

et al. 2022

Food Processing Preservation

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An absolute quantification of α-globulin in rice matrices based on the liquid chromatography-tandem mass spectrometry (LC-MS/MS) utilizing extended stable isotope-labeled (SIL) peptides were studied. Two modified signature peptides, derived from the cysteine-specific modification by IAA during the tryptic digestion process, were identified and selected as the surrogates of α-globulin due to the 1.5-4.5-fold

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“…A 10-g sample was mixed with 20 mL of water and titrated with 0.1 M NaOH using phenolphthalein as an indicator ( 19 ). The control was under the same conditions without the sample.…”

Section: Methodsmentioning

confidence: 99%

Inhibition of Advanced Glycation End Products in Yogurt by Lotus Seedpod Oligomeric Procyanidin

Feng

Shen

et al. 2021

Front. Nutr.

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The basic ingredients of yogurt include lactose and protein. Yogurt undergoes the Maillard reaction easily, producing many advanced glycation end products (AGEs) that cause some chronic diseases. Lotus seedpod oligomeric procyanidin (LSOPC) have demonstrated a strong inhibitory effect on AGE formation in simulated models; however, the inhibition of procyanidin on AGE formation and the subsequent effects on yogurt quality remains unknown. Our study demonstrated that LSOPC had a good inhibitory effect on the formation of fluorescent AGEs and Nε-carboxymethyl lysine (P < 0.05). The inhibitory capacity on AGEs and antioxidant activity of yogurt were positively correlated with the concentration of LSOPC. The effect of LSOPC on the physicochemical properties of yogurt was also evaluated. Bound water content, viscosity, and flavor of yogurt were significantly increased after LSOPC addition (P < 0.05). Therefore, LSOPC may lead to significant benefits for controlling AGE formation and improving the quality of yogurt.

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High-throughput quantification of eighteen heterocyclic aromatic amines in roasted and pan-fried meat on the basis of high performance liquid chromatography-quadrupole-orbitrap high resolution mass spectrometry

Cited by 70 publications

References 40 publications

Biomass magnetic porous carbon prepared from mangosteen shell for the preconcentration of three bisphenols from beverages followed by liquid chromatography with quadrupole‐Orbitrap high‐resolution mass spectrometry determination

Biomass magnetic porous carbon prepared from mangosteen shell for the preconcentration of three bisphenols from beverages followed by liquid chromatography with quadrupole‐Orbitrap high‐resolution mass spectrometry determination

Quantification of rice α‐globulin allergen using liquid chromatography–tandem mass spectrometry combined with cysteine‐specific modifier and extended stable isotope‐labeled peptide

Inhibition of Advanced Glycation End Products in Yogurt by Lotus Seedpod Oligomeric Procyanidin

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