High yield of glucose from cassava starch hydrolysis by poly(4‐vinylpyridine) hydrochloride

Ramanandraibe, Voahangy; Rakotondramanga, Maonja Finaritra; Alson, Hervé Fidèle; Andriamirijatsimanadinosoa, Jean Vareine; Andrianjafy, Tovo Mbolatiana; Métay, Estelle; Lemaire, Marc

doi:10.1111/ijfs.14793

Cited by 3 publications

(1 citation statement)

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“…Cassava starch has also gained popularity as a potential starting material for glucose syrup manufacturing in the last decade, and it has been widely researched utilizing enzymatic, acid hydrolysis, or catalysts such as poly(4-vinylpyridine) hydrochloride (PVP, HCl), green clay activated with HCl, Amberlyst, Montmorillonite KSF, and zeolite [ 6 – 9 ]. Apart from starch, the industrialization of cassava has not seen any diversification until the introduction of high quality cassava flour (HQCF).…”

Section: Introductionmentioning

confidence: 99%

Pharmaceutical Applications of Glucose Syrup from High Quality Cassava Flour in Oral Liquid Formulations

Simpson

Owusu

Boakye-Gyasi

et al. 2022

International Journal of Food Science

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Pharmaceutical oral solutions are preparations in which the active ingredients are dissolved in suitable liquid vehicles such as syrups. This study sought to determine the potential of glucose syrup produced from high quality cassava flour (HQCF) as a vehicle or sweetener in the preparation of paracetamol syrup and simple linctus. Four formulations (two paracetamol syrups (B1 and B2) and two simple linctus formulations (A1 and A2)) were prepared using glucose syrup from HQCF as vehicle or sweetener while two controls (B3 and A3) were prepared for each group using sucrose syrup as vehicle or sweetener. Two brands of paracetamol syrup and simple linctus were purchased from retail pharmacies to serve as standards. Physical and organoleptic parameters such as pH, taste and color, microbial load, and drug content of all formulations were determined. All formulations passed the microbial load and drug content tests as specified by the British Pharmacopoeia. The paracetamol syrups were all sweet with characteristic bitter aftertastes except formulation B2 which was sweetened with sucralose. All the simple linctus formulations were sweet except A2 (sweetened with sucralose) which was very sweet. The taste masking capacity of the glucose syrup produced from HQCF matched that of the sucrose syrup in the products formulated. Therefore, glucose syrup from HQCF could be a suitable alternative to sucrose syrup as a vehicle or sweetener in oral liquid formulations and can ultimately reduce the cost of these oral liquid formulations.

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Section: Introductionmentioning

confidence: 99%