Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty

Lee, Anderson; Durst, Caleb R.; Rezzadeh, Kevin; Rajaee, Sean S.; Penenberg, Brad L.; Than, Justin

doi:10.1016/j.arth.2023.04.043

Cited by 9 publications

(2 citation statements)

References 32 publications

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“…However, the optimal interval between COVID-19 infection and elective TJA remains a matter of debate. In a large database series using matched controls, Lee et al found that patients who had a COVID-19 diagnosis 3 to 6 months before TJA were at an increased risk of readmission, pneumonia, and DVT compared with controls 36 . The risk of increased LOS and pneumonia was replicated in a similarly matched group of patients who had a COVID-19 infection within 3 months of surgery.…”

Section: Medical Implications Of Covid-19–infected Patients Undergoin...mentioning

confidence: 99%

The Impact of the COVID-19 Pandemic on the Practice of Hip and Knee Arthroplasty

Sniderman,

Abdeen

2023

JBJS Reviews

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» The COVID-19 global pandemic resulted in unprecedented disruptions in care including massive surgical cancelations, a shift to outpatient surgery, and novel medical risks posed by COVID-19 infection on patients undergoing joint replacement surgery.» Refined patient optimization pathways have facilitated safe, efficient outpatient total joint arthroplasty in patient populations that may not otherwise have been considered eligible.» Rapid innovations emerged to deliver care while minimizing the risk of disease transmission which included the widespread adoption of telemedicine and virtual patient engagement platforms.» The widespread adoption of virtual technology was similarly expanded to resident education and continuing medical activities, which has improved our ability to propagate knowledge and increase access to educational initiatives.» Novel challenges borne of the pandemic include profound personnel shortages and supply chain disruptions that continue to plague efficiencies and quality of care in arthroplasty and require creative, sustainable solutions.

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Section: Medical Implications Of Covid-19–infected Patients Undergoin...mentioning

confidence: 99%

The Impact of the COVID-19 Pandemic on the Practice of Hip and Knee Arthroplasty

Sniderman,

Abdeen

2023

JBJS Reviews

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“…37 Similarly, the US national database study reported by Lee et al, with 1940 and 5840 patients, respectively, compared post-operative complications following total joint arthroplasty in COVID and non-COVID ARD survivors. 38 Meanwhile, in one oft-cited paper that combined patients from two randomized controlled trials (RCTs), one RCT only had COVID cases recruited from multiple centers from April through June 2020, while the other RCT only had non-COVID patients recruited from entirely different centers from 2011 through 2017. 39 Moreover, very few of these studies assessed for predictors of mortality.…”

Section: Introductionmentioning

confidence: 99%

Comparing critically ill ARDS patients with COVID-19 vs. without COVID-19: A prospective, bivariate and multi-variable analysis of 690 patients

Algethamy,

Aboudeif,

Alhandi

et al. 2023

Anaesth. pain intensive care

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Background & objective: Few studies have directly and prospectively compared ICU patients with acute respiratory distress syndrome (ARDS) caused by COVID-19 vs. other causes. Almost all previously-published studies were retrospective and employed historical non-COVID cases. We aimed to identify and compare patient characteristics and predictors of mortality associated with COVID-related vs. non-CIVID-related ARDS. Methodology: We performed a prospective cohort study. Consecutive ARDS patients with or without confirmed COVID-19 admitted to an ICU of a major tertiary-care hospital from March-December 2020 were included. A total of 160 patients with ARDS and positive for COVID-19 and 530 ARDS patients without COVID-19 were enrolled. Data were collected and both bivariate and multivariable analyses performed on COVID-19 status, demographics, morphometrics, comorbidities, presenting symptoms, general health status (APACHE-II) on admission, respiratory parameters and laboratory tests at admission, within 24 h of admission, and pre-intubation. The treatment administered and outcomes were also recorded. Data capture was almost 100%. Results: Numerous clinical differences were detected between 160 patients with COVID-19 vs. 530 patients without COVID-19. Most notably, COVID-19 patients were generally older and heavier, much more frequently presented with fevers/chills, dyspnea, cough, anosmia/ageusia, and sore throat — and had worse outcomes. including over a two-fold rate of mortality and five-fold rate of survivors requiring prolonged supplemental oxygen. The presenting symptom dyad of fevers and/or chills and dyspnea was 93.0% sensitive and 63.4% specific for COVID-related ARDS. A baseline APACHE-II Score ≥ 17 and requiring mechanical ventilation was 94.4% sensitive and 70.5% specific for mortality. All 37 COVID patients with an APACHE-II score > 30 died, vs. survival among non-COVID patients with APACHE-II scores up to 40. Conclusion: In one of the first large studies to directly compare contemporary populations of COVID-19 and non-COVID ICU patients with ARDS, employing multi-variable analysis, numerous differences in patient characteristics, presentation, and outcomes were detected. Abbreviations: APACHE-II - Acute Physiologic Assessment and Chronic Health Evaluation 2nd edition; PaO2 - Partial Pressure of Oxygen; SaO2 - Arterial Oxygen Saturation; BUN - Blood Urea Nitrogen; ALT - Alanine Aminotransferase; AST - Aspartate Aminotransferase; LDH - Lactate Dehydrogenase; NIPPV - Non- Invasive Intermittent Positive Pressure Ventilation; HFNC - High-Flow Nasal Cannula; ECMO - Extra-Corporeal Membrane Oxygenation Key words: COVID-19; ARDS; Clinical Characteristics; Treatment; Outcomes; Predictors Citation: Algethamy HM, Aboudeif MM, Alhandi MO, Majrashi FY, Hakami SH, Jan MA, Kabli HA, Alhomrani MH, White KP. Comparing critically ill ARDS patients with COVID-19 vs. without COVID-19: A prospective, bivariate and multi-variable analysis of 690 patients. Anaesth. pain intensive care 2023;27(6):652−664; DOI: 10.35975/apic.v27i6.2355 Received: March 04, 2023; Revised: October 09, 2023; Accepted: October 25, 2023

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Response to Letter to Editor Regarding Article, ‘Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty’

Rosas

Pollock

Najafi

et al. 2023

The Journal of Arthroplasty

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Higher Complication Rate in COVID-19 Recovered Patients Undergoing Primary Total Joint Arthroplasty

Cited by 9 publications

References 32 publications

The Impact of the COVID-19 Pandemic on the Practice of Hip and Knee Arthroplasty

The Impact of the COVID-19 Pandemic on the Practice of Hip and Knee Arthroplasty

Comparing critically ill ARDS patients with COVID-19 vs. without COVID-19: A prospective, bivariate and multi-variable analysis of 690 patients

Response to Letter to Editor Regarding Article, ‘Patients With Previous COVID-19 Infection Can Safely Undergo Primary Total Joint Arthroplasty’

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