In this paper, different chromatic dispersion compensation schemes like pre-, post-, and symmetrical schemes are compared numerically in the presence of intrachannel four-wave mixing (IFWM) for return-to-zero quasi-linear transmission systems. The transmission performances have been compared in terms of the average intensity deviation of the "1" bits and the relative intensity of the ghost pulse (the "0" bits). It is found that, for a fixed amplifier spacing, optimal compensation scheme depends on transmission bit rate. As bit rate increases the performance of pre-compensation becomes better. On the contrary, post-compensation exhibits its advantage more and more as bit rate decreases.