Highly Efficient Adsorption of Phenylethanoid Glycosides on Mesoporous Carbon

Abstract

PhGs are the major active compounds of Cistanche tubulosa, and it is extremely desirable for obtaining high purification of PhGs by adsorption from their extracts. To explore highly efficient adsorption of PhGs, a novel adsorption material for the efficient separation and purification of phenylethanoid glycosides (PhGs) from Cistanche tubulosa was explored. The three mesoporous carbons of ordered mesoporous carbon (CMK-3), disordered mesoporous carbon (DMC), and three-dimensional cubic mesoporous carbon (CMK-8) were compared for adsorption of PhGs. Meanwhile, adsorption isotherms, adsorption kinetics, and the optimization of adsorption conditions were investigated. The results indicated that CMK-3 showed the highest adsorption capacity of 358.09 ± 4.13 mg/g due to its high specific surface area, large pore volume and oxygen-containing functional groups. The experimental data can be accurately described using the Langmuir model and pseudo-second-order model. The intra-particle diffusion model suggested that the rate-limiting steps of adsorption were intra-particle diffusion.

High‐Affinity Adsorbent with Honeycomb Structure for Efficient Acteoside Separation

“…All N 2 adsorption–desorption curves of CMC/PEI showed clear H3 hysteresis loops and type–IV behavior, suggesting that CMC/PEI were mesoporous adsorbents. [ 38,39 ] The specific surface area, pore volume, and pore size increased with increasing the molecular weight of PEI. Moreover, the specific surface area and pore parameters first increased and the decreased with increasing the addition amount of PEI (the molecular weight of 70 000).…”

Porous Graphitic Carbon-Based Imprint Mass Spectrometry Imaging with an Ambient Liquid Extraction Technique for Enhancing Coverage of Glycerolipids and Sphingolipids in Brain Tissue

“…This may be due to the fact that PGC represents different surface interactions in different solvent environments. It has been widely reported , that PGC adsorbents have shown an excellent ability for retaining extremely hydrophilic compounds in aqueous solution, such as sugars, glycans, glycopeptides, and hydrophilic peptides, due to special polar interactions. The polar retention may be due to an electron-pair donor–acceptor interaction or a charged-induced interaction between the pi-electrons of carbon and the polar groups .…”

“…Graphitic carbon materials, such as porous graphitic carbon (PGC), graphene, carbon nanotubes, and colloidal graphite, have a high surface area, high chemical stability, and various surface interactions . Graphitic carbon materials have been widely used to selectively capture or separate glycopeptides/glycoproteins and glycosides by hydrophilic interactions with glycosyl groups . Meanwhile, graphitic carbon materials were also used to separate glycerides from edible oil and enrich peptides from human serum by hydrophobic interactions.…”

“…23 Graphitic carbon materials have been widely used to selectively capture or separate glycopeptides/ glycoproteins and glycosides by hydrophilic interactions with glycosyl groups. 24 Meanwhile, graphitic carbon materials were also used to separate glycerides from edible oil 25 and enrich peptides from human serum 26 by hydrophobic interactions. PGC was reported to have an even stronger hydrophobic retention capability than C18 silica phases.…”

Design and Preparation of Molecularly Imprinted Membranes for Selective Separation of Acteoside

“…Acteoside (ACT) and echinacoside (ECH) are the index composition of PhGs, and the structures of ACT and ECH are similar (Cui et al, 2016b;Morikawa et al, 2019;Wu C. J. et al, 2019). At present, the main separation and purification methods of PhGs are the chromatography, the membrane separation technique, and adsorption method (Han et al, 2012;Dong et al, 2015;Pei et al, 2019;Xu et al, 2019b). High-speed countercurrent chromatography has low yield and low efficiency.…”