Highly Efficient Enantioresolution of 2,2-Dimethyl-3-hexanol with Cholamide Crystals on the Basis of Intercalation and Bilayer Inversion

Abstract

Enantioresolution of racemic 2,2-dimethyl-3-hexanol in solid state was achieved with four kinds of crystalline matrices of cholamide, yielding its S enantiomer in high purity and yields. This intercalation method accompanied bilayer inversion on their lipophilic sides.

Deoxycholamide Crystalline Frameworks as a Platform of Highly-Efficient Fluorescence Materials

“…Particularly, OICs consisting of flexible molecules and labile hydrogen bonds make their host-frameworks possible to accommodate guest molecules with various sizes and shapes in the channels by changing and tuning their superstructures. For example, we revealed that a series of cholic acid derivatives form a wide variety of lattice frameworks depending on the guest molecules. , To date, excellent optoelectronic systems based on OICs and the related thin films have been reported for perhydrotriphenylene by Oelkrug, Hanack, et al, and deoxycholic acid (DCA) by Botta et al or Zheng and Coppens, independently. , In such systems, photophysical properties depending on the molecular arrangements, such as polarized emission and highly efficient excitation energy transfer between guest molecules, were achieved.…”