:
The role of oxindole derivatives is discussed as starting materials in diverse organic reactions including two and
more components between the years 2014 until 2020. Oxindoles are famous because of their biological properties for
instance chromanone-fused polycyclic pyrrolidinyl-dispirooxindoles, functionalized polycyclic spiro-fused
carbocyclicoxindole, and 3,3-disubstituted oxindoles have anti-cancer, anti-tumor, and anti-microbial properties,
respectively. Therefore, various methods for synthesizing the oxindole structures have received more attention in organic
chemistry.