Highly efficient method for oximation of aldehydes in the presence of bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides

Abstract

In this study, the selective oximation of structurally diverse aromatic aldehydes (versus ketones) to the corresponding aldoxime derivatives was investigated using the combination system of NH2OH•HCl and bis-thiourea complexes of cobalt, nickel, copper and zinc chlorides, M II (tu)2Cl2, in a mixture of CH3CN-H2O (1:1). All reactions were carried out successfully at room temperature within the immediate time up to 130 min giving the products in high yields. Investigation of the results exhibited that the applied bis-thiourea metal complexes represented the catalytic activity in order of Co(tu)2Cl2> Ni(tu)2Cl2> Cu(tu)2Cl2> Zn(tu)2Cl2 in their oximation reactions.