Highly Emissive Metal‐Organic Frameworks for Sensitive and Selective Detection of Nitrofuran and Quinolone Antibiotics

Abstract

The overuse of antibiotics makes its detection very significant for human health. New facile methods and high‐performance sensory materials will be urgently needed for detection of antibiotics. Unfortunately, there are few reports on fluorescence enhancement of antibiotics detection. Herein, based on the modulability of the coordination mode, we proposed two MOFs with different coordination modes based on different metal ions: Zn‐MOF (1) and Cd‐MOF (2). The fluorescence of 1 and 2 can be efficiently and selectively quenched by nitrofuran antibiotics (nitrofurazone, NFZ and furazolidone, FZD) and chloramphenicol (CAP), respectively. Particularly, the matched energy levels between 2 and enrofloxacin (ENR) enables 2 with turn‐on sensing for ENR. Moreover, apart from the sensitivity and selectivity, 1 and 2 also have strong recyclable ability, fast response time and anti‐interference ability, which make them great potential sensory materials to detect antibiotics.

A 3,8-connected Cd(ii)-based metal–organic framework as an appropriate luminescent sensor for the antibiotic sulfasalazine

“…Moreover, the phenomenon of photo-induced electron transfer (PET) is another well-known antibiotic quenching process, which comprises electron transfer from the luminescent framework (MOF) conduction band (CB) to the LUMOs of the antibiotics. 45–48 The CB of 1 is at a higher energy state than the LUMO of the antibiotic analytes, which results in electron transfer from the ligand to the antibiotics, causing fluorescence quenching. 49–52 Thus, overall, the quenching phenomenon can be ascribed to both the RET and PET processes.…”

A Novel Zn (II)‐Based Metal‐Organic Framework as a Highly Selective and Sensitive Luminescent Sensor for the Detection of Nitrofuran Antibiotics

“…And the quantum yield of H 4 TCPPDA in the solid state is almost 0 %, while that is 2.99 % for ZJU‐126 . The reason for the enhancement of luminescence is that the intramolecular rotation of the free ligand is limited due to the coordination between carboxyl group and zinc ion, thus reducing the loss of energy by radiationless decay [10b] . In the illustration, the resultant single microcrystal of ZJU‐126 exhibits blue green light FL emission under 365 nm UV excitation.…”

Anthracene‐Modified Cadmium Metal‐Organic Framework as an Excellent Sensor for the Detection of 2,4,6‐Trinitrophenol and Nitrofurantoin

“…The higher K SV value and lower detection limit make CUST-535 show greater advantages in MOF-based sensors. [37][38][39][40][41][42][43] (Table S4)…”