Highly ordered and robust honeycomb films with tunable pore sizes fabricated via UV crosslinking after applying improved phase separation

Bui, Van‐Tien; Lee, Hwa Su; Choi, Jae‐Hak; Choi, Ho‐Suk

doi:10.1016/j.polymer.2015.07.056

Cited by 25 publications

(18 citation statements)

References 35 publications

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“…An improved phase separation technique was also used by the application of a “base” polymer layer with a consequent dip coating technique [ 14 ]. This process (IPS) was developed for biocompatible and biodegradable PLLA, but was also tested for several other commercially available polymers, such as polymethylmethacrylate (PMMA) or polystyrene (PS) [ 14 ]. Honeycomb structures were also observed for PS using the breath figure (BF) method [ 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

PLLA Honeycomb-Like Pattern on Fluorinated Ethylene Propylene as a Substrate for Fibroblast Growth

et al. 2020

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In this study, we present the surface patterning of a biopolymer poly(l-lactide) (PLLA) for fibroblast growth enhancement. The patterning is based on a self-organized pore arrangement directly fabricated from a ternary system of a solvent-nonsolvent biopolymer. We successfully created a porous honeycomb-like pattern (HCP) on a thermally resistant polymer—fluorinated ethylene propylene (FEP). An important preparation step for HCP is activation of the substrate in Ar plasma discharge. The polymer activation leads to changes in the surface chemistry, which corresponds to an increase in the substrate surface wettability. The aim of this study was to evaluate the influence of the PLLA concentration in solution on the surface morphology, roughness, wettability, and chemistry, and subsequently, also on fibroblast proliferation. We confirmed that the amount of PLLA in solution significantly affects the material surface properties. The pore size of the prepared layers, the surface wettability, and the surface oxygen content increased with an increasing amount of biopolymer in the coating solution. The optimal amount was 1 g of PLLA, which resulted in the highest number of cells after 6 days from seeding; however, all three biopolymer concentrations exhibited significantly better results compared to pristine FEP. The cytocompatibility tests showed that the HCP promoted the attachment of cell filopodia to the underlying substrate and, thus, significantly improved the cell–material interactions. We prepared a honeycomb biodegradable support for enhanced cell growth, so the surface properties of perfluoroethylenepropylene were significantly enhanced.

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Section: Introductionmentioning

confidence: 99%

PLLA Honeycomb-Like Pattern on Fluorinated Ethylene Propylene as a Substrate for Fibroblast Growth

et al. 2020

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“…It has to be noted that the UV irradiation acts the functions of both crosslinking the PS domains and degrading the PMMA domains. [ 25–27 ] The porous PS/AAO substrates are then immersed in the freshly prepared AuNPs suspension for 6 h, by which the AuNPs are immobilized. The immobilization of the AuNPs is driven by both the van der Waals interactions and electrostatic interactions, caused by the naturally contained positive charges of AuNPs, inducing the spontaneous adhesion process.…”

Section: Figurementioning

confidence: 76%

Reproducible and Bendable SERS Substrates with Tailored Wettability Using Block Copolymers and Anodic Aluminum Oxide Templates

Lin

Karapala

Shen

et al. 2020

Macromol. Rapid Commun.

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further extended through well-designed SERS substrates. [5,6] Although many kinds of SERS substrates have been reported, extensive studies have mainly focused on enhancing the sensitivity by generating more SERS-active sites (commonly known as "hot spots") on the substrates using strategies such as colloidal assembly, lithography technique, and nanoimprinting. [7][8][9][10][11] Besides, the wetting properties of the SERS substrates have recently gained much attention. Typically, the SERS substrates that are covered with noble metals are naturally hydrophilic, which in turn restricts further applications such as trace analysis or single-molecule detection because of the low probability in locating the analyte molecules at SERS-active sites especially for highly diluted solutions. [12,13] To overcome the limitations, many strategies have been reported. For example, Yang et al. developed a method by aggregating target molecules and metal nanoparticles into small regions. [14] A slippery liquid-infused porous surface consisting of a Teflon membrane and a perfluorinated lubricant, which eliminates the adhesion of the droplets, was used. Such a surface was found to lead to a constant water contact angle (WCA) during the solvent evaporation process and enhance the aggregation efficiency of the gold nanoparticles (AuNPs) and the target molecules. In another example, Chen et al. demonstrated a strategy to achieve effective aggregation by applying the coffee ring effect using cellulose nanofibers (CNFs) and AuNPs. [15] Suspended analyte particles were carried and accumulated at the drop edges by the hydrodynamic flow, and eventually, formed ring-shape SERS sensitive regions. The CNF-AuNPs substrates were found to have a wider SERS detection zone (L D ≥ 300 µm) compared with the conventional method (L D ≤ 30 µm), which can be attributed to the unique surface properties. Park et al. also developed a facile protocol by placing the analyte molecules at the SERS-active nanogaps of the nanopillars to achieve high sensitivity. [16] By controlling the surface energy of plasmonic nanopillars through the selective removal process, a wide range of WCA from 165.8° (superhydrophobic surface) to 40.0° (hydrophilic surface) was obtained. Under the optimized wetting conditions, successful detection Surface properties are essential for substrates exhibiting high sensitivity in surface-enhanced Raman scattering (SERS) applications. In this work, novel SERS hybrid substrates using polystyrene-block-poly(methyl methacrylate) and anodic aluminum oxide templates is presented. The hybrid substrates not only possess hierarchical porous nanostructures but also exhibit superhydrophilic surface properties with the water contact angle ≈0°. Such surfaces play an important role in providing uniform enhanced intensities over large areas (relative standard deviation ≈10%); moreover, these substrates are found to be highly sensitive (limit of detection ≈10 −12 m for rhodamine 6G (R6G)). The results show that the hybrid SERS substrates can achieve the simu...

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“…Experimental details are described in Ref. [1] . The honeycomb PS films used in this work were prepared with chloroform/methanol ratio of 90/10, and under ambient air environment.…”

Section: Experimental Design Materials and Methodsmentioning

confidence: 99%

Data from crosslinked PS honeycomb thin film by deep UV irradiation

et al. 2015

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Thin polystyrene (PS) films with highly ordered honeycomb pattern were successfully fabricated by an improved phase separation method. The PS film was successfully crosslinked after applying a deep UV irradiation. This work presents a proof of crosslinking PS by characterizing ATR-FTIR, TGA and the wetting property of the honeycomb films, which were prepared using a solvent/non-solvent ratio of 90/10, before and after 6 h of UV irradiation.

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Highly ordered and robust honeycomb films with tunable pore sizes fabricated via UV crosslinking after applying improved phase separation

Cited by 25 publications

References 35 publications

PLLA Honeycomb-Like Pattern on Fluorinated Ethylene Propylene as a Substrate for Fibroblast Growth

PLLA Honeycomb-Like Pattern on Fluorinated Ethylene Propylene as a Substrate for Fibroblast Growth

Reproducible and Bendable SERS Substrates with Tailored Wettability Using Block Copolymers and Anodic Aluminum Oxide Templates

Data from crosslinked PS honeycomb thin film by deep UV irradiation

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