Highly ordered anodic porous alumina membrane and its surface modification approaches for biomedical application

Abstract

During recent years, the anodization of aluminum, due to its great commercial significance, represents one of the most important and widespread method used for the synthesis of ordered nanostructures. Whose geometry is controlled by diverse synthesis factors which include the voltage applied, the temperature of the electrochemical environment in which the synthesis is carried out, the reagent used to etch the aluminum metal and the time period of anodization. As anodic porous alumina (APA) has high porosity, pores with high aspect ratio with highly ordered pores. The matrix is well-suited for biomedical applications such as protein separation, purification, biomolecule detection, drug delivery protein crystallography and cell cultures because the biological macromolecules can easily fit into the pores of the matrix without the loss of primary biological action. In combination with surface engineering and nanobiotechnology diverse surface modifications are now being realized with nanoscale pore structures of APA that can provide high selectivity to archive a variety of applications based on specific molecular characteristics. This review observes how the structure and properties of APA related to their present and prospective uses for research in biotechnology. In addition, the role of APA are also covered in areas including, sensitive detection methods, microarrays and other molecular assays, and in creating new nanostructures for further uses within biology.

Amplified Charge Transfer for Anionic Redox Probes through Oriented Mesoporous Silica Thin Films

“…Transport phenomena involving small molecules/ions or macromolecules within nanopores have been largely studied by using nanoporous membranes, [1][2][3][4][5][6] mainly because of their great interest for applications in separation, [7] sensinga nd biosensing, [8][9][10] or medicald evices. [11] Compared with the widely used organic functional polymer membranes, [12] inorganic nanoporous materials (such as zeolites, [13] porous silicon, [14] anodized alumina, [15,16] mesoporous silica and related organicinorganic hybrids, [16][17][18] or someo thers [19] )o ffer the advantage of better control of the nanostructure and easier surface modification. [2,19,20] Mesoporouss ilica thin films on electrodes have recently attracted considerable attention,n otably in the field of electrochemicals ensorsa nd biosensors as well as energy conversion and storage.…”

Análisis cuantitativo del ordenamiento de alúmina anódica nanoporosa obtenida a diferentes potenciales de anodizado

“…La alúmina anódica nanoporosa (AAN) se ha convertido en una de las plataformas más utilizadas para producir varias nano-estructuras para aplicaciones en dispositivos magnéticos, electrónicos ý opticos [1]- [3]. Además, AAN es una plataforma adaptable para varios propósitos: obtención de sensores químicos yópticos [4], aplicaciones biomédicas [5], [6], almacenamiento de energía [7], cristales fotónicos [8], catálisis [9], [10], como reflector Bragg [11], sistemas de liberación de medicamentos [12], entre otros. La AAN se caracteriza por una estructura en forma de panal de abejas con arreglos de poros empaquetados inscritos en celdas columnares hexagonales [1], [13], [15], este alto grado de ordenamiento se ha convertido en una de las características más sobresalientes de la AAN, por lo que los esfuerzos de los investigadores se han concentrado en fabricar estructuras cada vez más ordenadas [16].…”