Highly sensitive and stable zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) glucose biosensor

Wu, Haiyan; Lee, Chen-Jung; Wang, Huifeng; Hu, Yang; Young, Megan; Han, Yu; Xu, Fu‐Jian; Cong, Hongbo; Cheng, Gang

doi:10.1039/c7sc05104b

Cited by 61 publications

(47 citation statements)

References 44 publications

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“…[1][2][3][4] Extensive research demonstrated that zwitterionic polymers and polymers containing poly(ethylene glycol) components (referred to as "PEG materials" in this article) exhibit excellent antifouling activities. [5][6][7][8][9] It is believed that the strong surface hydration of such polymers mediates their excellent antifouling performance. [10][11][12][13] With strong surface hydration, it is difficult for biological media (e.g., protein molecules, bacteria, marine organisms, etc.)…”

Section: Introductionmentioning

confidence: 99%

Surface hydration for antifouling and bio-adhesion

et al. 2020

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Section: Introductionmentioning

confidence: 99%

Surface hydration for antifouling and bio-adhesion

et al. 2020

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“…are highly tunable in nature and can be altered by merely substituting the monomers with donor/acceptor moieties to obtain emission in the near infrared (NIR) region. These conjugated polymers find promising applications in solar cells, 11 biosensing 12,13 and bioimaging. 14–16 Several investigations have been reported on the design of donor–acceptor based conjugated polymers for their potential application in bio-imaging and photodynamic therapy.…”

Section: Introductionmentioning

confidence: 99%

Development of a near infrared novel bioimaging agent via co-oligomerization of Congo red with aniline and o-phenylenediamine: experimental and theoretical studies

Singh

Kumar

et al. 2019

RSC Adv.

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With a view to study the effect of insertion of a multifunctional dye moiety on the photo physical properties of conducting polymers, the present paper reports for the first time the homopolymerization and cooligomerization of Congo red (CR) dye with aniline and o-phenylenediamine. The co-oligomerization was established by Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance spectroscopy ( 1 H-NMR), and ultraviolet-visible (UV-vis) spectroscopy while the morphology was examined using X-ray diffraction (XRD) and scanning electron microscopy (SEM) techniques. The theoretical as well as experimental data of 1 H-NMR as well as IR studies confirmed the co-oligomer formation while ultraviolet-visible spectroscopy studies revealed a dynamic change in the optical properties upon variation of co-oligomer composition. X-ray diffraction studies established a crystalline morphology of oligomers. Live cell confocal imaging studies revealed that the co-oligomers could be effectively used in NIR imaging.

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“…By this antifouling polymer coating, the sensor presents a high linearity ( R 2 = 0.9874) from 0.1 to 0.5 mM. In contrast to antifouling properties of PEDOT–GOx coating, PSBEDOT–GOx showed better antifouling properties for blood plasma and fibrinogen proteins [ 176 ].…”

Section: Semi-implantable Device For In Vivo Applicationsmentioning

confidence: 99%

Semi-Implantable Bioelectronics

et al. 2022

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Developing techniques to effectively and real-time monitor and regulate the interior environment of biological objects is significantly important for many biomedical engineering and scientific applications, including drug delivery, electrophysiological recording and regulation of intracellular activities. Semi-implantable bioelectronics is currently a hot spot in biomedical engineering research area, because it not only meets the increasing technical demands for precise detection or regulation of biological activities, but also provides a desirable platform for externally incorporating complex functionalities and electronic integration. Although there is less definition and summary to distinguish it from the well-reviewed non-invasive bioelectronics and fully implantable bioelectronics, semi-implantable bioelectronics have emerged as highly unique technology to boost the development of biochips and smart wearable device. Here, we reviewed the recent progress in this field and raised the concept of “Semi-implantable bioelectronics”, summarizing the principle and strategies of semi-implantable device for cell applications and in vivo applications, discussing the typical methodologies to access to intracellular environment or in vivo environment, biosafety aspects and typical applications. This review is meaningful for understanding in-depth the design principles, materials fabrication techniques, device integration processes, cell/tissue penetration methodologies, biosafety aspects, and applications strategies that are essential to the development of future minimally invasive bioelectronics.

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Highly sensitive and stable zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) glucose biosensor

Abstract: A zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT)-based glucose biosensor was fabricated via encapsulating glucose oxidase (GOx) in a one-step electropolymerization method.

Cited by 61 publications

References 44 publications

Surface hydration for antifouling and bio-adhesion

Surface hydration for antifouling and bio-adhesion

Development of a near infrared novel bioimaging agent via co-oligomerization of Congo red with aniline and o-phenylenediamine: experimental and theoretical studies

Semi-Implantable Bioelectronics

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