Highly sensitive electrocatalytic biosensing of hypoxanthine based on functionalization of graphene sheets with water-soluble conducting graft copolymer

Zhang, Jing; Lei, Jianping; Pan, Rong Jun; Xue, Yadong; Ju, Huangxian

doi:10.1016/j.bios.2010.07.127

Cited by 103 publications

(36 citation statements)

References 52 publications

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“…Graphene sheets also serve as good substrates for various other molecule detection, including acetylcholine/choline [42], cholesterol [43], benzenediol isomers (hydroquinone, resorcinol, catechol) [44], epinephrine [45], aromatic molecules (crystal violet, amaranth, phosphorus triphenyl [46], and rhodamine 6G, rhodamine B, methyl violet, methylene blue [47]), folic acid [48], naphthalene and 1-naphthol [49], malachite green [50], microcystin-LR [51], cocaine/adenosine [52], pyrogallol [53,54], nitric oxide [55], urea [56], hydrazine [57], nitrophenol [58], catechol [59], hypoxanthine [60], chlorite [61], paraoxon [62,63], phenol [64], heparin [65,66], trinitrotoluene (TNT) [67,68], bleomycin [69], ochratoxin A, and fumonisin B 1 [70].…”

Section: Other Moleculesmentioning

confidence: 99%

“…Exploring graphene-based composites as the platforms, various molecules have been detected using electrochemical (CV [55][56][57][58], CA [59][60][61][62][63][64], and ASV [67]), colorimetric [66], and fluorescent [65,[68][69][70] methods. For instance, Tu et al [61] introduced positively charged picket-fence porphyrin (FeTMAPP) to functionalize rGO with good biocompatibility and dispersibility in aqueous solution.…”

Section: Nadhmentioning

confidence: 99%

See 1 more Smart Citation

Graphene for Detection of Adenosine Triphosphate, Nicotinamide Adenine Dinucleotide, Other Molecules, Gas, and Ions

Han

et al. 2014

SpringerBriefs in Molecular Science

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Graphene-based electrochemical aptasensing platforms have been rapidly developed to detect different targets by combining various electrochemical techniques with aptamer-based signal conversion strategies. Electrochemical aptasensor for adenosine triphosphate (ATP) detection was recently realized by using functionalized graphene nanosheets. Nicotinamide adenine dinucleotide (NADH) is involved as a cofactor in hundreds of enzymatic reactions of NAD + /NADHdependent dehydrogenases. The mechanism of NADH oxidation was thoroughly studied on graphene platform. Graphene sheets also serve as good substrates for detection of various other molecules, including acetylcholine/choline, cholesterol, benzenediol isomers (hydroquinone, resorcinol, and catechol), and epinephrine. The unique structure and oxygenic functionalities of GO facilitate it to be easily turned into a potentially useful gas storage material and biological ionic and molecular channels. Functionalized nanopores in graphene monolayers were designed and used as ionic sieves with high selectivity and transparency. Some cations, such as Li Keywords Graphene Á Adenosine triphosphate Á Nicotinamide adenine dinucleotide Á Gas sensor Á Ion-selective sensor ATPAdenosine triphosphate (ATP), as the major carrier of chemical energy in living species, is an important substrate in living organisms, which plays a critical role in the regulation and integration of cellular metabolism. In addition, it has also been used as an indicator for cell viability and cell injury [1]. Therefore, the detection of ATP is highly important in biochemical study and clinic diagnosis. Electrochemical aptasensor represents an attractive choice, which is simple, rapid, and allows device miniaturization. Until now, graphene-based electrochemical aptasensing platforms

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Section: Other Moleculesmentioning

confidence: 99%

Section: Nadhmentioning

confidence: 99%

Graphene for Detection of Adenosine Triphosphate, Nicotinamide Adenine Dinucleotide, Other Molecules, Gas, and Ions

Han

et al. 2014

SpringerBriefs in Molecular Science

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“…4. Zhang et al [81] synthesized the functionalization of rGO sheets with conducting PPy graft copolymer, poly(styrenesulfonic acid-g-pyrrole), via π-π noncovalent interaction.…”

Section: Chemical Polymerizationmentioning

confidence: 99%

“…The determination of hypoxanthine is very essential for the quality control of fish products in food industries [111]. Zhang et al was designed a biosensing platform for hypoxanthine by the functionalization of rGO sheets with conducting PPy graft copolymer, poly(styrenesulfonic acid-g-pyrrole), via π-π non covalent interaction [81]. The biosensor exhibited a wide linear response ranging from 3.0 × 10 −8 to 2.8 × 10 −5 M with a high sensitivity of 673 ± 4 µA M −1 cm −2 and the detection limit of 10 nM.…”

Section: Enzymatic Biosensorsmentioning

confidence: 99%

Development of Biosensors from Polymer Graphene Composites

Dey

2015

Graphene-Based Polymer Nanocomposites in Electronics

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Graphene has been considered as excellent two dimensional support in recent-times for next-generation graphene-polymer composites towards the development of biosensors. The remarkable properties of polymer and graphene with respect to electrical, mechanical, optical and structural aspect offers an ideal composite support for the development of biosensor. The frontiers of this composites technology is by combining of the polymer and graphene through synergy to achieve the goal of enhanced performance of biosensors with good efficiency and cost effectiveness. Graphene combined with polymer enhances the performance of biosensors in terms of sensitivity, selectivity, response time, and multiplexing capability of biosensors for clinical diagnostics. In this chapter, various methods have been provided to produce the polymer-based graphene composite materials and also discussed the importance of the composite materials to the development of biosensors for clinically important analytes, DNAs, aptamers and immunosensors.

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“…H 2 O 2 generates in various enzymatic reactions. Zhang et al designed PSSA‐g‐PPY functionalized graphene to detect H 2 O 2 , which can also be used to detect hypoxanthine in fish samples 129. In addition, other small biomolecules such as quercetin,130 isoquercitrin, baicalin,131 cholesterol132 and ATP133 can also be detected with graphene film‐based biosensors.…”

Section: The Human‐like Senses and Feedbacksmentioning

confidence: 99%

Human‐Like Sensing and Reflexes of Graphene‐Based Films

et al. 2016

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Humans have numerous senses, wherein vision, hearing, smell, taste, and touch are considered as the five conventionally acknowledged senses. Triggered by light, sound, or other physical stimulations, the sensory organs of human body are excited, leading to the transformation of the afferent energy into neural activity. Also converting other signals into electronical signals, graphene‐based film shows its inherent advantages in responding to the tiny stimulations. In this review, the human‐like senses and reflexes of graphene‐based films are presented. The review starts with the brief discussions about the preparation and optimization of graphene‐based film, as where as its new progress in synthesis method, transfer operation, film‐formation technologies and optimization techniques. Various human‐like senses of graphene‐based film and their recent advancements are then summarized, including light‐sensitive devices, acoustic devices, gas sensors, biomolecules and wearable devices. Similar to the reflex action of humans, graphene‐based film also exhibits reflex when under thermal radiation and light actuation. Finally, the current challenges associated with human‐like applications are discussed to help guide the future research on graphene films. At last, the future opportunities lie in the new applicable human‐like senses and the integration of multiple senses that can raise a revolution in bionic devices.

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Highly sensitive electrocatalytic biosensing of hypoxanthine based on functionalization of graphene sheets with water-soluble conducting graft copolymer

Cited by 103 publications

References 52 publications

Graphene for Detection of Adenosine Triphosphate, Nicotinamide Adenine Dinucleotide, Other Molecules, Gas, and Ions

Graphene for Detection of Adenosine Triphosphate, Nicotinamide Adenine Dinucleotide, Other Molecules, Gas, and Ions

Development of Biosensors from Polymer Graphene Composites

Human‐Like Sensing and Reflexes of Graphene‐Based Films

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