Highly Sensitive Reporter Gene Assay for Dioxins in Human Plasma by Using Cycloheximide as an Enhancer Substance

Saito, Koichi; Matsunaga, Haruyuki; Ohmura, Atsuko; Takekuma, Mikiko; Matsuki, Yasuhiko; Nakazawa, Hiroyuki

doi:10.2116/analsci.25.1029

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…Around this time, Freud described the famous case of Rat Man and popularized psychoanalytic explanations and therapy for OCD. 12 In the mid-20th century, learning theories became popular and led to behavioral 13,14 and cognitive therapy for OCD. 15 In parallel, neurobiological explanations of OCD were beginning to unfold.…”

Section: Historical Backgroundmentioning

confidence: 99%

Obsessive-compulsive disorder for ICD-11: proposed changes to the diagnostic guidelines and specifiers

Simpson

Reddy

2014

Rev. Bras. Psiquiatr.

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Since the approval of the ICD-10 by the World Health Organization (WHO) in 1990, global research on obsessive-compulsive disorder (OCD) has expanded dramatically. This article evaluates what changes may be needed to enhance the scientific validity, clinical utility, and global applicability of OCD diagnostic guidelines in preparation for ICD-11. Existing diagnostic guidelines for OCD were compared. Key issues pertaining to clinical description, differential diagnosis, and specifiers were identified and critically reviewed on the basis of the current literature. Specific modifications to ICD guidelines are recommended, including: clarifying the definition of obsessions (i.e., that obsessions can be thoughts, images, or impulses/urges) and compulsions (i.e., clarifying that these can be behaviors or mental acts and not calling these “stereotyped”); stating that compulsions are often associated with obsessions; and removing the ICD-10 duration requirement of at least 2 weeks. In addition, a diagnosis of OCD should no longer be excluded if comorbid with Tourette syndrome, schizophrenia, or depressive disorders. Moreover, the ICD-10 specifiers (i.e., predominantly obsessional thoughts, compulsive acts, or mixed) should be replaced with a specifier for insight. Based on new research, modifications to the ICD-10 diagnostic guidelines for OCD are recommended for ICD-11.

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Section: Historical Backgroundmentioning

confidence: 99%

Obsessive-compulsive disorder for ICD-11: proposed changes to the diagnostic guidelines and specifiers

Simpson

Reddy

2014

Rev. Bras. Psiquiatr.

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Pharmaceutical Analysis of Chemicals Related with Daily Life Products for Safe and Secure

Nakazawa

2014

YAKUGAKU ZASSHI

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An association between exposure to trace hazardous chemicals such as endocrine disrupting chemicals and an increased incidence of human endocrine disease might be continued to study. The accurate and sensitive analytical methods for determination of various chemicals in human biospecimen such as urine, blood and breast milk have been studied by techniques including chromatography. In order to obtain the safe and secure life, the pharmaceutical analytical approaches might be applicable with the hopes of realizing scientiˆc risk assessment of the chemicals derived from daily life products as regulatory sciences.Key words-pharmaceutical analysis; hazardous chemical; human biospecimen; daily life product; safe and secure

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Highly Sensitive Reporter Gene Assay for Dioxins in Human Plasma by Using Cycloheximide as an Enhancer Substance

Cited by 2 publications

References 19 publications

Obsessive-compulsive disorder for ICD-11: proposed changes to the diagnostic guidelines and specifiers

Obsessive-compulsive disorder for ICD-11: proposed changes to the diagnostic guidelines and specifiers

Pharmaceutical Analysis of Chemicals Related with Daily Life Products for Safe and Secure

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