Highly stable glucose oxidase polynanogel@MXene/chitosan electrochemical biosensor based on a multi-stable interface structure for glucose detection

Tong, Xinglai; Jiang, Lin; Ao, Qi; Lv, Xiaoxiao; Song, Ying; Tang, Jun

doi:10.1016/j.bios.2023.115942

Cited by 15 publications

(2 citation statements)

References 25 publications

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“…The 0.3 mg of weight was optimized by testing different weights (0.1, 0.3, and 0.5 mg), as shown in Figures S1 and S2. 0.3 mg of GOx was coated on CP and then allowed to dry naturally at room temperature Scheme depicts the entire process of material synthesis and electrode preparation.…”

Section: Methodsmentioning

confidence: 99%

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EGFET-Based Noninvasive Glucose Sensor Integrated with Enzyme-Mimicking Bi₂O₃ Microrods Derived from Bi-BTC Tested in Artificial Sweat

Shabanur Matada,

Kuppuswamy,

Martinez

et al. 2024

ACS Appl. Electron. Mater.

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For diabetic patients, effective glucose monitoring is critical, which makes the development of inexpensive, enzyme-free, and nonintrusive glucose sensors necessary. Conventional techniques have not been consistent, necessitating intricate instrumentation and protocols that drive up prices, impede downsizing, and take too long. The presented research attempts to develop a stable Bi 2 O 3 (bismuth oxide)-sensing electrode derived from Bi-BTC [bismuth (Bi)�1,3,5-benzenetricarboxylic acid (BTC)]. This electrode operates through an extended gate field-effect transistor configuration and is designed to facilitate noninvasive glucose monitoring. This electrode exhibits a high sensitivity of 351.68 μA mM −1 cm −2 , a limit of detection of 3.7 μM, and a quick response time of less than 5 s in 1× phosphate-buffered saline, effectively covering a linear range from 20 to 1300 μM. The Bi-BTC-derived Bi 2 O 3 -sensing electrode follows Michaelis− Menten kinetics in response to glucose, with a K m value of 0.86 mM, which is lower than the K m value of 0.89 mM for glucose oxidase, implying that Bi 2 O 3 has strong affinity toward glucose. Most remarkably, we used measurements with a scanning Kelvin probe to show a relationship between the glucose response and the electrode's work function. Additional research using standard artificial sweat has demonstrated the excellent recovery of the Bi-BTC-derived Bi 2 O 3 -sensing electrode. Overall, our findings have shown how well the prepared electrode can quickly detect sweat glucose levels, providing encouraging opportunities for the noninvasive diagnosis of diabetes mellitus.

show abstract

Section: Methodsmentioning

confidence: 99%

“…0.3 mg of GOx was coated on CP and then allowed to dry naturally at room temperature. 63 Scheme 1 depicts the entire process of material synthesis and electrode preparation.…”

Section: Introductionmentioning

confidence: 99%

EGFET-Based Noninvasive Glucose Sensor Integrated with Enzyme-Mimicking Bi₂O₃ Microrods Derived from Bi-BTC Tested in Artificial Sweat

Shabanur Matada,

Kuppuswamy,

Martinez

et al. 2024

ACS Appl. Electron. Mater.

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Recent Developments in MXene-Based Enzyme-Free Electrochemical Glucose Sensing

Le,

Cho

2024

BioChip J

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An ultrasensitive electrochemical/colorimetric dual-mode self-powered biosensing platform for lung cancer marker detection by multiple-signal amplification strategy

Song,

Guo,

Mao

et al. 2024

Analytica Chimica Acta

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Highly stable glucose oxidase polynanogel@MXene/chitosan electrochemical biosensor based on a multi-stable interface structure for glucose detection

Cited by 15 publications

References 25 publications

EGFET-Based Noninvasive Glucose Sensor Integrated with Enzyme-Mimicking Bi₂O₃ Microrods Derived from Bi-BTC Tested in Artificial Sweat

EGFET-Based Noninvasive Glucose Sensor Integrated with Enzyme-Mimicking Bi₂O₃ Microrods Derived from Bi-BTC Tested in Artificial Sweat

Recent Developments in MXene-Based Enzyme-Free Electrochemical Glucose Sensing

An ultrasensitive electrochemical/colorimetric dual-mode self-powered biosensing platform for lung cancer marker detection by multiple-signal amplification strategy

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Highly stable glucose oxidase polynanogel@MXene/chitosan electrochemical biosensor based on a multi-stable interface structure for glucose detection

Cited by 15 publications

References 25 publications

EGFET-Based Noninvasive Glucose Sensor Integrated with Enzyme-Mimicking Bi2O3 Microrods Derived from Bi-BTC Tested in Artificial Sweat

EGFET-Based Noninvasive Glucose Sensor Integrated with Enzyme-Mimicking Bi2O3 Microrods Derived from Bi-BTC Tested in Artificial Sweat

Recent Developments in MXene-Based Enzyme-Free Electrochemical Glucose Sensing

An ultrasensitive electrochemical/colorimetric dual-mode self-powered biosensing platform for lung cancer marker detection by multiple-signal amplification strategy

Contact Info

Product

Resources

About

EGFET-Based Noninvasive Glucose Sensor Integrated with Enzyme-Mimicking Bi₂O₃ Microrods Derived from Bi-BTC Tested in Artificial Sweat

EGFET-Based Noninvasive Glucose Sensor Integrated with Enzyme-Mimicking Bi₂O₃ Microrods Derived from Bi-BTC Tested in Artificial Sweat