Hip Pain in an 18-year-old Man

Orthopaedic · Radiology · Pathology Conference: Painful Distal Femur Lesion in a 13-year-old Girl

“…Plain radiographs or CT scans may show mineralization in an osteoblastoma but not in a GCT. Aneurysmal bone cysts have a higher incidence in patients younger than 20 years [22,28]. Aneurysmal bone cysts may need to be excluded after histologic evaluation but often expand the bone greater than GCTs on radiography [33].…”

“…Histologically, microscopic calcifications are often prominent, showing the appearance of a chicken-wire fence [30]. Immunostaining for S-100 is positive in chondroblastomas [28] and negative in GCT. Chondroblastoma has a higher incidence in skeletally immature individuals and young adults and frequently has a sclerotic rim not typical of GCT [33].…”

“…Chondroblastoma has a higher incidence in skeletally immature individuals and young adults and frequently has a sclerotic rim not typical of GCT [33]. Chondromyxoid fibroma is a benign cartilaginous tumor typically affecting individuals between the second and third decades of life [28]. Chondromyxoid fibroma is located mostly in the metaphyses of the long bones [8].…”

“…Chondromyxoid fibromas do not typically have calcifications. The histologic features of chondromyxoid fibroma are characterized by clustered stellate chondroid cells in a myxoid background forming lobules that are separated by fibrous septae [8,28].…”