Hipotiroidismo y daño miocárdico en donantes cardíacos

Haldon, José López; Martı́nez, Ángel; Ordóñez, Antonio; Marques, Júlio Cezar; Borrego, J.M.; Serrera, J.L.

doi:10.1016/s0300-8932(01)76388-9

Cited by 4 publications

(1 citation statement)

References 13 publications

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“…These observations have led to increased interest in the clinical application of thyroid hormone replacement as a therapeutic approach to promote hemodynamic stability and improve cardiac function. In humans, reduced levels of thyroid hormone and thyroid-stimulating hormone (TSH) have not been consistently reported after brain death (136,137,160,174,175). Even when present, low levels of circulating thyroid hormone are not always associated with hemodynamic instability.…”

Section: When Should Thyroid Replacement Therapy Be Considered?mentioning

confidence: 99%

Management of the Potential Organ Donor in the ICU

Kotloff

Blosser

Fulda

et al. 2015

Critical Care Medicine

279

150

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This document was developed through the collaborative efforts of the Society of Critical Care Medicine, the American College of Chest Physicians, and the Association of Organ Procurement Organizations. Under the auspices of these societies, a multidisciplinary, multi-institutional task force was convened, incorporating expertise in critical care medicine, organ donor management, and transplantation. Members of the task force were divided into 13 subcommittees, each focused on one of the following general or organ-specific areas: death determination using neurologic criteria, donation after circulatory death determination, authorization process, general contraindications to donation, hemodynamic management, endocrine dysfunction and hormone replacement therapy, pediatric donor management, cardiac donation, lung donation, liver donation, kidney donation, small bowel donation, and pancreas donation. Subcommittees were charged with generating a series of management-related questions related to their topic. For each question, subcommittees provided a summary of relevant literature and specific recommendations. The specific recommendations were approved by all members of the task force and then assembled into a complete document. Because the available literature was overwhelmingly comprised of observational studies and case series, representing low-quality evidence, a decision was made that the document would assume the form of a consensus statement rather than a formally graded guideline. The goal of this document is to provide critical care practitioners with essential information and practical recommendations related to management of the potential organ donor, based on the available literature and expert consensus.

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Section: When Should Thyroid Replacement Therapy Be Considered?mentioning

confidence: 99%

Management of the Potential Organ Donor in the ICU

Kotloff

Blosser

Fulda

et al. 2015

Critical Care Medicine

279

150

View full text Add to dashboard Cite

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Assessment of the Potential Heart Donor

Dronavalli

Banner

Bonser

2010

Journal of the American College of Cardiology

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Demand for donor hearts exceeds supply, and a significant number of patients die while awaiting transplantation. Within the pool of currently unused potential donor hearts, a proportion may be suitable for transplantation but are declined due to anticipated poor function. Despite current assessment methods, in some donor hearts accepted for transplantation early graft failure develops in the recipient. Current methods of assessment are inadequate, and there is a potential for biomarkers to improve identification of satisfactory hearts for transplantation or hearts destined to fail in the recipient. Biomarkers are routinely used to diagnose and risk-stratify myocardial infarction, acute coronary syndromes, and heart failure. Some of these might facilitate donor heart assessment. Cardiac troponins, cytokines, inflammatory markers, natriuretic peptides, and intracellular proteins may each have discriminant value. This review details the current status of biomarkers in the assessment of donor hearts.

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