Hipovitaminosis D y factores asociados a los 4 años en el norte de España

Rodríguez-Dehli, Ana Cristina; Riaño‐Galán, Isolina; Fernández-Somoano, Ana; Navarrete-Muñoz, Eva María; Espada, Mercedes; Vioque, Jesús; Tardón, Adonina

doi:10.1016/j.anpedi.2016.02.003

Cited by 10 publications

(8 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Second, prior studies rarely examined preschool children, and in most investigations where preschoolers were included, they formed part of the larger sample (i.e., preschool and school-age children) [ 64 ]. In addition, in previous investigations of only preschoolers, indicators of obesity were not related to 25(OH)D levels [ 65 ]. Therefore, although the relationship between indicators of adiposity and 25(OH)D status has been frequently confirmed in somewhat older children and adolescents, whether it truly exists in this age group remains questionable [ 60 , 61 , 62 , 64 ].…”

Section: Discussionmentioning

confidence: 85%

Vitamin D Status and Analysis of Specific Correlates in Preschool Children: A Cross-Sectional Study in Southern Croatia

Karin

Gilić

Domić

et al. 2018

IJERPH

View full text Add to dashboard Cite

Vitamin D deficiency is a globally important problem, particularly in children, but there is a lack of information regarding this deficiency in preschool children from southeastern Europe. This study aimed to establish the levels of 25-hydroxyvitamin D (25(OH)D) and associations of gender, time spent outdoors, physical activity (PA), and body mass index (as predictors) with the 25(OH)D level (outcome) in healthy preschool children. The participants were preschoolers (all 5–6 years of age) from southern Croatia. All the participants were tested during their mandatory medical examination 6–7 months prior to school enrollment. The PA was obtained using the preschool-age physical activity questionnaire (Pre-PAQ), which categorizes PA into five levels (from sedentary to vigorous PA). The prevalence of 25(OH)D deficiency was high: 58% of the children had 25(OH)D levels of <50 nmol/L (deficiency), and an additional 29% had an insufficient level of 25(OH)D (50–75 nmol/L). Boys had higher levels of 25(OH)D than girls. A multinomial regression using 25(OH)D categories as the outcome and a sufficient level (>75 nmol/L) as the reference value identified gender as the only significant predictor of 25(OH)D status, with boys being at lower risk for 25(OH)D deficiency than girls. These results showed a high prevalence of 25(OH)D deficiency in preschoolers from the southern part of Croatia, which is additionally alarming based on the geographical position of the studied region (42° N) and its high number of sunshine hours (>2600 h per year). Future studies examining other potential correlates of 25(OH)D in the region are warranted.

show abstract

Section: Discussionmentioning

confidence: 85%

Vitamin D Status and Analysis of Specific Correlates in Preschool Children: A Cross-Sectional Study in Southern Croatia

Karin

Gilić

Domić

et al. 2018

IJERPH

View full text Add to dashboard Cite

show abstract

“…These studies relied on parents’ reporting of their child’s or the mother’s diet during pregnancy, without any direct measurement of serum vitamin D levels. As we have previously reported, the children of the INMA-Asturias birth cohort were characterized by a significant vitamin D deficiency in the mother during pregnancy [ 35 ], and in the child at 4 years of age [ 34 ]. Our study results indicated that vitamin D levels in the child at 8 years were consistent with prenatal levels in the mother.…”

Section: Discussionmentioning

confidence: 99%

“…For all these reasons and given the possibly significant role of vitamin D in the development of dentition in children, we proposed to study the influence of vitamin D levels during pregnancy and the first years of life on dental anomalies in children between 6 and 10 years of age. Previously, our research group evaluated the concentration of 25(OH) D in children and mothers of the INMA-Asturias birth cohort and reported a significant deficiency in these children at 4 years of age and their mothers during pregnancy [ 34 , 35 ]. We also assessed how the concentration of 25(OH) D in the mother influenced the development of children’s social competence [ 36 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Vitamin D, pregnancy and caries in children in the INMA-Asturias birth cohort

et al. 2021

Self Cite

View full text Add to dashboard Cite

Background Vitamin D is traditionally associated with the metabolism of calcium and phosphorus, a process essential for the mineralization of hard tissue such as bone or tooth. Deficiency of this vitamin is a problem worldwide, however. Given the possibly significant role of Vitamin D in odontogenesis in children, the objective of our study was to determine the influence of vitamin D levels in the blood on dental anomalies in children between 6 and 10 years of age, by means of 25-hydroxy vitamin D tests performed during pregnancy and the first years of life. Methods The data analyzed were sourced from data belonging to the INMA-Asturias birth cohort, a prospective cohort study initiated in 2004 as part of the INMA Project. The 25-hydroxy vitamin D (25(OH)D) test was performed with samples from 188 children in the INMA-Asturias birth cohort with a dental examination performed between 6 and 10 years of age. The samples were taken at three stages: in the mother at 12 weeks of gestation, and subsequently in the child at 4 and 8 years of age. Diet, nutritional and oro-dental hygiene habits were also analyzed by means of questionnaires. Results The results indicate a significant association between caries and correct or incorrect brushing technique. With incorrect brushing technique, the prevalence of caries was 48.89%, but this dropped to 22.38% with correct brushing technique. An association was also found between tooth decay and frequency of sugar intake. The prevalence of caries was 24.54% with occasional sugar intake, but this rose to 56% with regular sugar intake. On the other hand, levels < 20 ng/ml in both mother and child at 8 years of age would also be risk factors (ORgest = 2.51(1.01–6.36) and OR8years = 3.45(1.14–11.01)) for the presence of caries in children. The risk of caries practically tripled where 25(OH) D values were < 20 ng/ml. Conclusions Although incorrect brushing technique and regular sugar consumption was found to be the main cause of caries in the children, the low concentrations of vitamin D in the blood of the pregnant mothers may have magnified this correlation, indicating that the monitoring of vitamin D levels during pregnancy should be included in antenatal programmes. It is particularly striking that 50% of the children were deficient in vitamin D at the age of 4, and that dental floss was practically absent from regular cleaning routines.

show abstract

“…In fact, retinol concentration is highly regulated by liver stores over a wide range of dietary intakes that can affect serum levels. Also, it has been suggested that plasma concentrations of α-tocopherol may not be a good marker of vitamin E for usually intake in children, and 25OHD may be a poor biomarker of dietary vitamin D since the absorption can be influenced for the sunlight exposure [45,46].…”

Section: Discussionmentioning

confidence: 99%

Reproducibility and Validity of a Short Food Frequency Questionnaire for Dietary Assessment in Children Aged 7–9 Years in Spain

et al. 2019

View full text Add to dashboard Cite

The purpose of this study was to examine if the short semi-quantitative food frequency questionnaire (FFQ) is a reliable and valid tool to assess the diet of Spanish children aged 7–9 years. We collected data from 156 children of the birth cohort INMA (Infancia y Medio Ambiente (Environment and Childhood)). Children’s parents or care-givers completed a 46-item FFQ on two occasions over a 9–12-month period about the children’s diet. To explore the reproducibility of the FFQ, the nutrient and food group intake collected from the both FFQs were compared, while validity was examined by contrasting the nutrient values from the FFQs and the average of three 24-hour dietary recalls (24hDRs) taken in this period, and also with the concentration of several vitamins in the blood (carotenoids, vitamin D and α-tocopherol). Pearson and de-attenuated correlation coefficients were calculated. The average correlation coefficients for nutrient intake’s reproducibility was 0.41, ranging from 0.25 (calcium) to 0.65 (β-carotene), and for food group intake was 0.45, ranging from 0.18 (cereals) to 0.68 (sweetened beverages). Correlation coefficients slightly improved when we compared energy-adjusted intakes. The average correlation coefficients for validity against 24hDRs was 0.34 for energy-adjusted intakes, and 0.39 when de-attenuation coefficients were used. The validity coefficients against the blood concentrations of vitamins were 0.38 for β-cryptoxanthin, 0.26 for lycopene, 0,23 for α-carotene and 0.15 for β-carotene, all of them statistically significant (p < 0.05). This study suggests that our brief FFQ is a suitable tool for the dietary assessment of a wide range of nutrients and food groups in children 7–9 years, despite the low to moderate reproducibility and validity observed for some nutrients.

show abstract

Hipovitaminosis D y factores asociados a los 4 años en el norte de España

Cited by 10 publications

References 32 publications

Vitamin D Status and Analysis of Specific Correlates in Preschool Children: A Cross-Sectional Study in Southern Croatia

Vitamin D Status and Analysis of Specific Correlates in Preschool Children: A Cross-Sectional Study in Southern Croatia

Vitamin D, pregnancy and caries in children in the INMA-Asturias birth cohort

Reproducibility and Validity of a Short Food Frequency Questionnaire for Dietary Assessment in Children Aged 7–9 Years in Spain

Contact Info

Product

Resources

About