Hippocampal metabolic profile during epileptogenesis in the pilocarpine model of epilepsy
Letícia Meier,
Estevan Bruginski,
Joseane Righes Marafiga
et al.
Abstract:Temporal lobe epilepsy (TLE) is a common form of refractory epilepsy in adulthood. The metabolic profile of epileptogenesis is still poorly investigated. Elucidation of such a metabolic profile using animal models of epilepsy could help identify new metabolites and pathways involved in the mechanisms of epileptogenesis process. In this study, we evaluated the metabolic profile during the epileptogenesis periods. Using a pilocarpine model of epilepsy, we analyzed the global metabolic profile of hippocampal extr… Show more
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