Hippocampus, Temporal Context and Taste Memories

Molero, A.; Morón, Ignacio; Ballesteros, María Ángeles; Manrique, Tatiana; Fenton, André A.; Gallo, M.

doi:10.1093/chemse/bjm089

Cited by 3 publications

(3 citation statements)

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“…The safe taste memory dependence on protein synthesis in the hippocampus opens the exciting possibility of other relations between items besides time and space being processed and consolidated in the hippocampus. However, and not less interesting, it remains to be shown whether context is a relevant component of safe taste memory as was previously suggested (Gallo, 2005). Gallo et al.…”

Section: Discussionmentioning

confidence: 86%

“…Differences in time of day in which acquisition and tests took place impaired the expression of long‐term safe taste memory. Importantly, this effect may be mediated by the hippocampus as lesions to this area disturbed time‐dependent effects on safe taste memory (Gallo, 2005). On the other hand, aversive taste memories are particularly emotional and other components may become dispensable, i.e.…”

Section: Discussionmentioning

confidence: 99%

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Medial temporal lobe structures participate differentially in consolidation of safe and aversive taste memories

Cruz

Rodriguez‐Ortiz

Balderas

et al. 2008

Eur J of Neuroscience

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Taste memories are amongst the most important kinds of memories, as adequate identification of safe and toxic edibles will determine the subject's survival. Despite the well-established role that the medial temporal lobe plays in consolidation of memory, specific contributions of the different regions of the temporal lobe to taste memory consolidation remain unknown. In the present report, we assessed the participation of perirhinal cortex (Ph), dorsal hippocampus (Hipp), basolateral (BLA) and central nuclei of the amygdala (CeA) in safe and aversive taste memories by means of local infusions of the protein synthesis inhibitor anisomycin in the rat. The results showed that protein synthesis in the CeA, but not BLA, is required to stabilize taste aversion memory. Surprisingly, the Ph and Hipp seem to be essential to consolidate safe taste memory. These data suggest that different networks within the temporal lobe are recruited to consolidate memory depending on the consequences associated with tastes.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Medial temporal lobe structures participate differentially in consolidation of safe and aversive taste memories

Cruz

Rodriguez‐Ortiz

Balderas

et al. 2008

Eur J of Neuroscience

View full text Add to dashboard Cite

show abstract

“…Acredita-se que a memória genuinamente espacial em animais seja um tipo de memória "explícita", por envolver o mesmo substrato neuro-anatômico da memória declarativa dos humanos e pela sua natureza flexível, já que permite a operação por atalhos, quando disponíveis. De fato, diversos estudos mostram o papel do sistema hipocampal no processamento da memória contextual (JARRARD, 1993;REIS et al, 1999;MAREN & HOLT, 2000;RICHMOND & COLOMBO, 2002;GALLO, 2005), que envolve a lembrança de um evento ("o quê") associado às pistas espaciais ("onde") e/ou intrínsecas (como cores ou padrão de cores) do ambiente em que foi adquirido; pombos e ratos, cujo hipocampo foi lesado, treinados a discriminar diferentes situações de reforço em diferentes contextos, apresentam prejuízos no seu desempenho em relação ao controle, fato atribuído à inabilidade desses animais lesados em utilizar as pistas contextuais do ambiente na discriminação (GOOD & HONEY, 1991;JARRARD, 1993;RICHMOND & COLOMBO, 2002). Propõe-se que os animais formem "mapas cognitivos" do ambiente, isto é, constructos neurais que representariam os objetos e suas relações num dado ambiente (TOLMAN, 1932apud XAVIER, 1986.…”

Section: A) Aprendizagem E Memória Nos Animaisunclassified