2024
DOI: 10.1038/s12276-023-01145-3
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HIRA vs. DAXX: the two axes shaping the histone H3.3 landscape

Jinmi Choi,
Taewan Kim,
Eun-Jung Cho

Abstract: H3.3, the most common replacement variant for histone H3, has emerged as an important player in chromatin dynamics for controlling gene expression and genome integrity. While replicative variants H3.1 and H3.2 are primarily incorporated into nucleosomes during DNA synthesis, H3.3 is under the control of H3.3-specific histone chaperones for spatiotemporal incorporation throughout the cell cycle. Over the years, there has been progress in understanding the mechanisms by which H3.3 affects domain structure and fu… Show more

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Cited by 4 publications
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