1998
DOI: 10.1097/00024382-199802000-00003
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Histamine Receptor Antagonists, Cyclooxygenase Blockade, and Tumor Necrosis Factor During Acute Septic Insult

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Cited by 13 publications
(11 citation statements)
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“…However, in a recent study, it was clearly demonstrated that the selective COX-2 inhibitor rofecoxib attenuated LPS-induced cardiovascular failure [10]. Furthermore, promising results with the COX inhibitor ibuprofen were achieved in some previous studies [25, 28]. …”
Section: Discussionmentioning
confidence: 99%
“…However, in a recent study, it was clearly demonstrated that the selective COX-2 inhibitor rofecoxib attenuated LPS-induced cardiovascular failure [10]. Furthermore, promising results with the COX inhibitor ibuprofen were achieved in some previous studies [25, 28]. …”
Section: Discussionmentioning
confidence: 99%
“…H 2 antagonists impair neutrophil rolling in vitro (510), while other studies have shown the presence of immunostimulatory properties of H 2 antagonists (280,343,448). In preterm neonates, effects of H 2 antagonists and proton pump inhibitors on neutrophil function or cytokine production are probably overshadowed by their effect on pH and gastrointestinal tract colonization with potential pathogens.…”
Section: Susceptibility Of Very-low-birth-weight Infants To Infectionmentioning
confidence: 99%
“…The drug does not affect the cerebral blood flow [3,[7][8]. Reports on the effect of IB on the immune system revealed attenuation of certain sepsisinduced alterations [9], while others have found opposite results [10].…”
Section: Introductionmentioning
confidence: 97%
“…The reports on the effect of IB on the cytokine production are controversial. Some investigators have reported an increased proinflammatory cytokine secretion [13][14][15], while others have found that it was reduced [9,16,17] or unchanged [18].…”
Section: Introductionmentioning
confidence: 99%