Histamine storage and metabolism of human liver in disorders of the biliary tract

Barth, H.; Kapp, Bruce S.; Crombach, M.; Priesack, W.; Lorenz, W.

doi:10.1007/bf02024187

Cited by 5 publications

(2 citation statements)

References 22 publications

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“…By far the highest activities of any tissue were found in the liver which is in agreement with BARTH et al [1]. By far the highest activities of any tissue were found in the liver which is in agreement with BARTH et al [1].…”

Section: Hmt Activity In Human Tissuessupporting

confidence: 88%

Histamine content, diamine oxidase activity and histamine methyltransferase activity in human tissues: Fact or fictions?

et al. 1984

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To understand the role of histamine in the aetiology and pathogenesis of human diseases reliable data are urgently needed for the histamine content and for the activities of histamine-forming and -inactivating enzymes in human tissues. In order to make a substantial progress toward this aim a tissue-sampling programme during surgical interventions was carefully conceived and conducted. From March 1982 until January 1983 106 tissue specimens were taken from 56 patients who underwent surgery. Only healthy tissues, not injured or oedematous, and without adherent structures were taken by only one surgeon who was interested in this research and experienced in tissue preparation procedures in biochemistry. The times of 'warm' ischaemia during the operative procedures were visually estimated, the times between resection of the organs or specimens and deep-freezing of the tissues were precisely recorded. Compared to previous work in the literature and especially to our own work using the same assays for determination higher histamine contents were found in this study in most of the tissues, in particular in the gastrointestinal tract. Also the diamine oxidase activities were considerably higher in many organs, e.g. 3-4 times higher in the gastrointestinal tract when compared with those in publications of our group who used always the same analytical test. However, the histamine methyltransferase activities in this study were not at variance to those determined in previous investigations. Many of them were reported in this communication for the first time. Since the methods for histamine determination and those for measuring enzymic activities were not different in this study and in previous communications of our group we are convinced that the optimized tissue-sampling and -preparation techniques were responsible for the higher values in this communication. But the problem of the 'warm' ischaemia period could not be solved by sample-taking procedures of this type during operations. There are good reasons to prefer biopsy specimens for the analysis of histamine storage and metabolism in human tissues in health and disease, but - unfortunately - they are not always available.

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Section: Hmt Activity In Human Tissuessupporting

confidence: 88%

Histamine content, diamine oxidase activity and histamine methyltransferase activity in human tissues: Fact or fictions?

et al. 1984

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“…Although the rats maintained with soybean diet had less growth than those maintained with casein diet, their organs weight/body weight ratios were similar, except for the liver that was reduced. However, the unchanged serum AST and ALT concentrations discard the possibility of liver cell damage for both acute and chronic hepato-cellular injuries [43]. The reduced liver weight may be explained by the low glycogen concentration observed in rats maintained with soybean diet (Oliveira EA, Veloso RV, Arantes VC, Carneiro EM, Boschero AC, Latorraca MQ., unpublished results) and/or by reduced triglyceride accumulation in the liver or may be due to the reduction of lipogeneses [44].…”

Section: Discussionmentioning

confidence: 99%

O efeito da farinha de soja na recuperação do estado nutricional e na secreção de insulina de ratos submetidos a restrição protéica durante a vida intra-uterina e na lactação

Veloso¹,

Carneiro²

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A Deus, por continuar a iluminar meu caminho em todas as paragens.Aos meus pais João Veloso do Carmo Filho (in memoriam) e Doralice Vilela Veloso, que embora distantes não mediram esforços para me mostrar uma vida digna e de caráter.Ao Prof. Dr. Everardo Magalhães Carneiro, que desde o início nos incentivou e fez despertar o nosso interesse pela pesquisa na área de Fisiologia.A Profª Drª Márcia Queiroz Latorraca, pela co-orientação em todas as etapas desse trabalho, demonstrando muita dedicação e profissionalismo para conosco.Ao Prof. Dr. Antonio Carlos Boschero, pela amizade e a quem considero meu segundo pai. Pesquisador íntegro e de competência intransponível.Aos professores da UNICAMP, em especial a Profª Drª Helena Coutinho Franco de Oliveira e Prof. Dr. Miguel Arcanjo Areas pela estima e por compartilharem da nossa formação científica.

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Kooperative ECR-Konzepte zur Steigerung der Effizienz und Effektivität im Absatzkanal

Schmickler¹

2001

Management Strategischer Kooperationen Zwischen Hersteller Und Handel

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Histamine storage and metabolism of human liver in disorders of the biliary tract

Cited by 5 publications

References 22 publications

Histamine content, diamine oxidase activity and histamine methyltransferase activity in human tissues: Fact or fictions?

Histamine content, diamine oxidase activity and histamine methyltransferase activity in human tissues: Fact or fictions?

O efeito da farinha de soja na recuperação do estado nutricional e na secreção de insulina de ratos submetidos a restrição protéica durante a vida intra-uterina e na lactação

Kooperative ECR-Konzepte zur Steigerung der Effizienz und Effektivität im Absatzkanal

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