Histiocytic Necrotizing Lymphadenitis (Kikuchi's Disease)

Piccirillo, Jay F.; Lanza, Donald C.; Stasio, Edward A.; Moloy, Peter J.

doi:10.1001/archotol.1991.01870190112024

Cited by 17 publications

(9 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Until now, nine cases of pregnancy‐related KFD have been reported (Table 1). 2–9 In these cases, no miscarriages were communicated. In some cases 2,6,9 KFD was diagnosed before pregnancy and it recurred during the next pregnancy.…”

Section: Discussionmentioning

confidence: 88%

See 1 more Smart Citation

Recurrent Kikuchi–Fujimoto disease during pregnancy: Report of case evolving into systemic lupus erythematosus and review of published work

Alijotas‐Reig

Casellas-Caro

Ferrer‐Oliveras

et al. 2008

J of Obstet and Gynaecol

View full text Add to dashboard Cite

Kikuchi-Fujimoto disease (KFD) is a distinctive, benign type of necrotizing lymphadenitis. KFD is a rare entity, especially during pregnancy. Although first described in Japan, subsequently it has been reported in the West. We communicate herein a case of KFD in African women with bouts during pregnancy. Diagnosis was difficult because peripheral enlarged lymph nodes were absent and an extended differential diagnosis and adequate work-up was necessary. The patient suffered a miscarriage coinciding with a KFD bout. Further pregnancies were uneventful. Follow up showed that KFD evolved into a systemic lupus erythematosus-like syndrome.

show abstract

Section: Discussionmentioning

confidence: 88%

“…The most frequent clinical complaints are cervical lymphadenopathy, high fever and chills. Although KFD affects young women of reproductive age, only few cases have been reported during pregnancy 2–9 . It has a self‐limiting clinical course, but recurrence has been described 2,6,9 .…”

Section: Introductionmentioning

confidence: 99%

Recurrent Kikuchi–Fujimoto disease during pregnancy: Report of case evolving into systemic lupus erythematosus and review of published work

Alijotas‐Reig

Casellas-Caro

Ferrer‐Oliveras

et al. 2008

J of Obstet and Gynaecol

View full text Add to dashboard Cite

show abstract

“…An autopsy of this case revealed multifocal myocyte necrosis, but the relationship to HNL was un clear. The cause of Kikuchi's disease is as yet unknown, although various infective agents have been postulated but none have been confirmed [1,4,5,12,13].…”

Section: Discussionmentioning

confidence: 99%

Histiocytic Necrotizing Lymphadenitis (Kikuchi’s Disease) of the Cervical Lymph Nodes

Kumar¹,

Walsh²,

Walter³

et al. 1997

ORL

View full text Add to dashboard Cite

show abstract

“…6 A flulike prodrome with fever is present in 30-50% of cases. 6,8,16 The following are less common symptoms: headache, nausea, vomiting, malaise, fatigue, weight loss (10%), 12 night sweats, chill (4%), 12 abdominal or chest pain 6 and fever of unknown origin. 17 Systemic symptoms are found more frequently when extranodal involvement is present.…”

Section: Clinical Manifestationmentioning

confidence: 99%

“…8,9 Several viral candidates have been proposed, including cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes virus 6 and 8, varicela zoster virus, parainfluenza virus, parvovirus B 19, myxovirus, 6 rubella, 10 Toxoplasma and Yersinia also have been reported as possible causative agents. 6,8,15,16,20 However, serologic and molecular studies have failed to link KFD to a specific pathogen 6,9 because several other studies that, by using the same and other molecular pathology procedures to localize the virus genome, have concluded that neither EBV nor herpes virus 6 or 8 has a putative role in the pathogenesis of KFD. 8,21 Chan et al 22 reported that, there is probably no one single cause for this lesion, and it is probably a hyperimmune reaction to different etiological agents, be it microbial, chemical, physical or neoplastic.…”

Section: Pathophysiologymentioning

confidence: 99%