Histologic Appearance of Endometriosis Infiltrating Uterosacral Ligaments in Women with Painful Symptoms

Bonte, Hélène; Chapron, Charles; Vieira, Marco; Barakat, Habib; Fritel, Xavier; Vacher-Lavenu, M. C.; Dubuisson, Jean

doi:10.1016/s1074-3804(05)60530-0

Cited by 54 publications

(25 citation statements)

References 21 publications

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“…Despite cyclical neovascularisation and major changes in growth, mean microvascular density remains static as claimed by Rogers [21] and that is the reason why we did not take into account the date of the cycle. Regarding endometriotic lesions, we confirm the wide heterogeneity of histopathologicals aspects of the endometriotic lesions, described by other authors [22][23][24]. Besides the fact that it has been impossible to select enough patients because of too numerous progestin treatment protocols, we were able to show a different intensity in the response due to progestin in the three tissues under study.…”

Section: Discussionsupporting

confidence: 86%

Image analysis measurements of the microvascularisation in endometrium, superficial and deep endometriotic tissues

2006

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Section: Discussionsupporting

confidence: 86%

Image analysis measurements of the microvascularisation in endometrium, superficial and deep endometriotic tissues

2006

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“…The importance of adequate treatment is strictly linked to the need for a correct diagnosis. Therefore, another issue that needs to be considered when estimating the prevalence of the disease depends on the diagnosis of endometriosis, which is surgical [27] and initially based on standardized macroscopic visual criteria [28]. For this reason, depending on the surgeon’s skill and on laparoscopic indications, endometriosis may be over- or under-diagnosed [29].…”

Section: Discussionmentioning

confidence: 99%

Spatial Analysis of the Distribution of Endometriosis in Northwestern Italy

Migliaretti

Deltetto²,

Delpiano³

et al. 2011

Gynecol Obstet Invest

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Objective: The aim of this study is to estimate the incidence of endometriosis in a northwestern region of Italy. The potential sources of geographical variations in the incidence of endometriosis within the region are discussed. Methods: The patients selected were women between 18 and 45 years of age, born and residing in Piedmont who had undergone medical or surgical treatment for endometriosis between 2000 and 2005. The data were obtained from official hospital discharge records. Results: The number of women contributed to the study was 3,929. The age-standardized incidence rate of endometriosis was 81.8/100,000 patient-years (95% CI 79.1–84.2). The distribution of relative risks showed some areas with an increased rate of around 30% (southern and central Piedmont), while for other areas the disease risk was lower (southwestern Piedmont). These areas have greater exposure to environmental risk due to the presence of chemical pollutants. Conclusion: In order to achieve reliable data and good management of the disease, there is great need for national registers, as well as networks of excellence for the treatment of endometriosis. Our findings suggest that environmental factors may be associated with the development of the disease, but the observed results need to be cautiously interpreted in the context of ineligible biases.

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“…A previous study 24 has underlined the low accuracy of macroscopic findings especially in women with superficial peritoneal endometriosis. However, recent reports have demonstrated the high accuracy of surgical findings for the diagnosis of deep pelvic endometriosis 25,26 .…”

Section: Discussionmentioning

confidence: 99%