Histologic Evidence of Distal Coronary Thromboembolism

Primary percutaneous intervention for acute occlusion of a native coronary artery may be complicated by distal embolization of plaque or thrombotic debris, with infarct extension. We tested the clinical application of a new therapeutic strategy combining maximal antiplatelet therapy, with glycoprotein IIb/IIIa inhibition, and adjunctive mechanical protection from distal embolization and direct aspiration of thrombus with a new balloon and catheter system (PercuSurgetrade mark). Successful aspiration of thrombus could be obtained in 7 out of 8 attempted procedures, with inability to negotiate the angulated take-off of the circumflex coronary artery in one patient. The current mechanical characteristics of the device, primarily developed for use in larger saphenous vein grafts, and certain caveats and limitations are discussed. New dedicated systems should be available in the near future for the native coronary circulation. Excellent immediate angiographic results were obtained in all treated patients, without evidence of loss of distal branches and no intraprocedural complications.

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Adjunctive thrombus aspiration and mechanical protection from distal embolization in primary percutaneous intervention for acute myocardial infarction

Belli

Pezzano

Biase

et al. 2000

Cathet. Cardiovasc. Intervent.

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Distal protection in native coronary arteries during primary angioplasty in acute myocardial infarction: Single‐center experience

Orrego

Delgado

Piccalò

et al. 2003

Cathet Cardio Intervent

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Spontaneous coronary artery dissection in a young man with anterior myocardial infarction

Yeoh¹,

Choo²,

Soo³

et al. 1991

Cathet. Cardiovasc. Diagn.

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Histologic Evidence of Distal Coronary Thromboembolism

Cited by 7 publications

References 6 publications

Adjunctive thrombus aspiration and mechanical protection from distal embolization in primary percutaneous intervention for acute myocardial infarction

Adjunctive thrombus aspiration and mechanical protection from distal embolization in primary percutaneous intervention for acute myocardial infarction

Distal protection in native coronary arteries during primary angioplasty in acute myocardial infarction: Single‐center experience

Spontaneous coronary artery dissection in a young man with anterior myocardial infarction

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