2022
DOI: 10.20517/2574-1209.2021.78
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Histological analysis of thrombi retrieved after acute ischemic stroke from large vessel occlusion: from research to clinical practice

Abstract: Emergent reperfusion therapies have improved acute ischemic stroke prognosis, but many patients are still bound to bad clinical outcome, probably because of our incomplete knowledge of its pathophysiology. Thanks to mechanical thrombectomy, occluding material is available for histological analysis. Several studies investigated the possible relationship between thrombus composition and clinical, procedural, and radiological variables of acute ischemic stroke. The potential value of thrombus analysis as a tool f… Show more

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“…While successful recanalization is a therapeutic goal, for 30% of stroke patients who achieve complete reperfusion it is not conducive to good clinical outcomes [ 101 ]. Better outcomes have been associated with greater clot perviousness, shorter thrombi, and a shorter procedural time [ 97 ].…”
Section: Clot Composition and Clinical Outcomesmentioning
confidence: 99%
“…While successful recanalization is a therapeutic goal, for 30% of stroke patients who achieve complete reperfusion it is not conducive to good clinical outcomes [ 101 ]. Better outcomes have been associated with greater clot perviousness, shorter thrombi, and a shorter procedural time [ 97 ].…”
Section: Clot Composition and Clinical Outcomesmentioning
confidence: 99%