Histological and Clinical Appraisal of Distribution and Long Acting New Hyaluronic Acid into the Subcutaneous Fat of the Forehead to Improve Horizontal Lines

Abramo, Antonio Carlos; Sgarbi, Romulo; Scartozzoni, Marcio

doi:10.1007/s00266-020-01906-9

Cited by 4 publications

(2 citation statements)

References 14 publications

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“…Dynamic forehead lines can be ameliorated using neuromodulators, commonly known as botulinum toxin, or by permanent denervation of the temporal branches of the facial nerve. [5][6][7][8] Static forehead lines can be indirectly treated using neuromodulators or denervation, as the decreased movement of the forehead relaxes the skin and causes a progressive amelioration of static forehead lines. 2,6,9 However, in some instances, the static forehead lines are too deep, which requires the use of soft-tissue fillers, most commonly hyaluronic acid-based soft tissue fillers.…”

Section: Introductionmentioning

confidence: 99%

Novel Validated Five-point Photonumeric Scales for Assessment of Static and Dynamic Forehead Lines

Lim,

Kerscher,

Ogilvie

et al. 2023

Plastic and Reconstructive Surgery - Global Open

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Background: The objective of this investigation was to create and validate five-point photonumeric scales which assess static and dynamic forehead lines. Methods: Two different novel five-point photonumeric scales for the assessment of static and dynamic forehead lines were developed. Moreover, a photoguide was created, including subjects from both sexes, all age groups, and different Fitzpatrick skin types. A total of 11 raters from all over the world were involved in the digital validation, whereas four raters performed a live validation. Results: The Croma Static Forehead Lines–Assessment Scale showed almost perfect inter and intra-rater agreement in both the digital and the live setting with inter-rater intraclass correlation coefficients of 0.86 [95% confidence interval (CI): 0.82–0.89] in the first digital rating and 0.82 [95% CI: 0.78–0.86] in the second digital rating. The Croma Dynamic Forehead Lines–Assessment Scale showed almost perfect inter and intra-rater agreement in the digital setting with inter-rater intraclass correlation coefficients of 0.83 [95% CI: 0.79–0.86] in the first digital rating and 0.80 [95% CI: 0.75–0.84] in the second rating and almost substantial agreement in the live setting. Conclusions: The Croma Static Forehead Lines–Assessment Scale and the Croma Dynamic Forehead Lines–Assessment Scale have excellent inter and intra-rater agreements to be justifiably used in the clinical and study setting, both digitally and live across ethnic groups.

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Section: Introductionmentioning

confidence: 99%

Novel Validated Five-point Photonumeric Scales for Assessment of Static and Dynamic Forehead Lines

Lim,

Kerscher,

Ogilvie

et al. 2023

Plastic and Reconstructive Surgery - Global Open

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“…The rough appearance of the surface, with different degrees of skin pigmentation greatly influences the self-esteem and daily lives of burn patients. Laser, conservative treatment, and surgery are frequently used for treating burns in clinics [3]. Skin grafting is a treatment method often used for extensive scars.…”

Section: Introductionmentioning

confidence: 99%

Effect of the combination of composite skin grafting and recombinant human basic fibroblast growth factor on plastic surgery for extensive sc ars after burns

Liu¹,

Zhang²

2022

Trop. J. Pharm Res

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Purpose: To investigate the effect of combined use of composite skin grafting and recombinant human basic fibroblast growth factor (rh-bFGF) on plastic surgery for extensive burn scars, and its influence on wound healing and inflammatory responses in patients. Methods: Hospital records of 120 patients who underwent extensive scar plastic surgery after burns in Hanchuan People’s Hospital from February 2019 to February 2020 were retrospectively analyzed. The patients were equally assigned to study group (STG) and control group (COG), based on the order of admission. All patients received composite skin grafting surgery and post-surgery topical silver sulphadiazine cream regularly, while those in study group (STG) received additional treatment with rh-bFGF spray on the wound surfaces. Scar scores, degree of wound healing, populations of fibrocytes and capillaries, levels of vascular endothelial growth factor (VEGF) and transforming growth factor-β1 (TGF-β1), and activities of lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) were evaluated. Results: Patients in STG had significantly better scar scores, shorter mean wound healing time, higher mean degree of wound healing, higher scores on inflammatory reactions near the wounds, and higher populations of fibrocytes and capillaries, when compared with patients in COG group (p < 0.001). After surgery, there were lower levels of VEGF and TGF-β1, and lower levels of activities of LDH and SDH in STG than in COG group (p < 0.001). Conclusion: Rh-bFGF accelerates the proliferation of wound tissue, improves local microcirculation, regulates inflammatory response, and enhances wound healing in burn scar patients when used in combination with composite skin grafting. Therefore, Rh-bFGF has a potential for enhanced management of burn scars.

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Application of High-Frequency Ultrasound to Evaluate Forehead Filling Materials

Yuan,

Zhuang,

Zheng

et al. 2024

Aesth Plast Surg

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Histological and Clinical Appraisal of Distribution and Long Acting New Hyaluronic Acid into the Subcutaneous Fat of the Forehead to Improve Horizontal Lines

Cited by 4 publications

References 14 publications

Novel Validated Five-point Photonumeric Scales for Assessment of Static and Dynamic Forehead Lines

Novel Validated Five-point Photonumeric Scales for Assessment of Static and Dynamic Forehead Lines

Effect of the combination of composite skin grafting and recombinant human basic fibroblast growth factor on plastic surgery for extensive sc ars after burns

Application of High-Frequency Ultrasound to Evaluate Forehead Filling Materials

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