Histological and Histomorphometrical Determination of the Biogradation of β-Tricalcium Phosphate Granules in Maxillary Sinus Floor Augmentation

Abstract

Highly pure β-TCP is a safe bone-grafting material with superior osteoconductive properties. Histologic and radiographic examinations indicate that β-TCP is slowly resorbed, which results in unresorbed graft material remaining even 6 months after the procedure, and that new bone replacement occurs slowly for approximately 1 year.

Sinus floor elevation using tricalcium phosphate plate

“…In another study, the TCP that was grafted into the maxillary sinus was absorbed, albeit in a very slow manner; it was replaced with new bone in about 6 months to 1 year [10]. However, in the current case report, a TCP-like radio-opacity was clearly observed on the CBCT image at 1 year, and the TCP degradation process could take longer than 1 year.…”

Randomized clinical trial for the biological evaluation of two nanostructured biphasic calcium phosphate biomaterials as a bone substitute

“…Because ß‐TCP‐based compounds exhibit a better organic response either alone or in combination with osteogenic substances, along with their biocompatibility and osteoconductive potential, several studies have compared their biological behavior as a bone substitute based on scientific evidence from commercially available materials . It was shown previously that the bioactivity of these biomaterials is related to the respective amounts of HA and ß‐TCP in each compound .…”

“…According to one study on the use of BoneCeramic in the maxillary 19,25 Because ß-TCP-based compounds exhibit a better organic response either alone or in combination with osteogenic substances, along with their biocompatibility and osteoconductive potential, several studies have compared their biological behavior as a bone substitute based on scientific evidence from commercially available materials. 18,[26][27][28][29][30][31] It was shown previously that the bioactivity of these biomaterials is related to the respective amounts of HA and ß-TCP in each compound. 32 Some clinical studies have shown the advantages of alveolar filling immediately after tooth extraction for the preservation of bone architecture for subsequent implant placement.…”

Evaluation of maxillary sinus floor augmentation with the crestal approach and beta-tricalcium phosphate: a cone-beam computed tomography 3- to 9-year follow-up

“…The β-TCP used in this study has only osteoconductive properties during absorption. Okada et al [20] reported that in maxillary sinus floor augmentation with the lateral approach, β-TCP was slowly replaced by new bone during the year after the graft was received. In this study, dome-shaped β-TCP was observed immediately after surgery, and the CBCT image decreased at follow-up.…”