1993
DOI: 10.1111/j.1365-2605.1993.tb01156.x
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Histological and Histopathological Evaluation of the Testis

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Cited by 1,166 publications
(1,715 citation statements)
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“…After 30 min, approximately 10% from each pole of a testis was removed and placed in 5 ml of fresh Bouin's ®xative at 48C for 24 h. After washing with 70% ethanol the testes were processed for embedding in para n wax. Several sections (4 mm) were mounted onto microscopic slides and stained with hematoxylin-eosin and visualized by light microscopy as described (Russell et al, 1990).…”
Section: Histocytochemistrymentioning
confidence: 99%
“…After 30 min, approximately 10% from each pole of a testis was removed and placed in 5 ml of fresh Bouin's ®xative at 48C for 24 h. After washing with 70% ethanol the testes were processed for embedding in para n wax. Several sections (4 mm) were mounted onto microscopic slides and stained with hematoxylin-eosin and visualized by light microscopy as described (Russell et al, 1990).…”
Section: Histocytochemistrymentioning
confidence: 99%
“…These junctions constitute the major component of the blood-testis barrier, and this barrier creates an immunoprivileged environment within the seminiferous tubules. When spermatogonia enter meiosis and become spermatocytes, the tight junctions are broken down and reformed to allow spermatocytes to translocate apically, complete meiosis and differentiate into spermatids in the immunoprivileged adluminal portion of the seminiferous tubules 1 . Consequently, when germ cells are introduced into recipient seminiferous tubules during the germ cell transplantation procedure, spermatogonial stem cells translocate in a basal direction through the tight junctions, towards the basement membrane of the seminiferous tubule.…”
Section: Germ Cell Transplantation and Colonizationmentioning
confidence: 99%
“…Spermatogenesis is a dynamic, continuous process in which diploid spermatogonia undergo ten mitotic and two meiotic divisions to differentiate into haploid spermatozoa 1 . This process generates a remarkable number of mature sperm -200 million per day in the human male -and requires an intimate association of germinal cells and somatic Sertoli cells within the seminiferous tubules of the testis.…”
mentioning
confidence: 99%
“…Mammalian spermatozoan development is a complex process that involves the proliferation and differentiation of spermatogonia, the meiosis of spermatocytes, and drastic morphological changes that occur during the progression from round spermatids to mature sperm [1]. Complete understanding of mammalian spermatogenesis is not easy because we have still not identified the structure or function of many of the genes that are involved in this process.…”
Section: Introductionmentioning
confidence: 99%
“…The five most frequent domains are the C2H2, PHD finger, KRAB-box, LIM and RING finger domains. RING finger proteins are characterized by the presence of a cysteine-rich domain (CX2CX CX [1][2][3]HX [2][3] CX2CX CX2C) and are involved in many biological processes, including signal transduction, transcriptional regulation, apoptosis and ubiquitination [5][6][7]. npg As one of the most versatile cellular regulatory mechanisms, ubiquitination is involved in many physiological and pathological events, including spermatogenesis, fertilization and sperm quality control [8,9].…”
Section: Introductionmentioning
confidence: 99%