Histological and imaging features of myoepithelial carcinoma of the bone and soft tissue

Aiba, Hisaki; Righi, Alberto; Spinnato, Paolo; Longhi, Alessandra; Frega, Giorgio; Atherley O’Meally, Ahmed; Aso, Ayano; Solou, Konstantina; Dozza, Barbara; Gambarotti, Marco; Ibrahim, Toni; Donati, Davide Maria; Errani, Costantino

doi:10.1007/s00256-024-04693-5

Skeletal Radiol

2024

DOI: 10.1007/s00256-024-04693-5

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Histological and imaging features of myoepithelial carcinoma of the bone and soft tissue

Hisaki Aiba,

Alberto Righi,

Paolo Spinnato

et al.

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2024

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Cited by 2 publications

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18F-FDG PET/CT Imaging of Myoepithelial Carcinoma in the Left Femur

Huang,

Xie,

Huang

2024

Clin Nucl Med

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Myoepithelial carcinoma of bone is uncommon. We presented the imaging features of myoepithelial carcinoma of the left femur in a 61-year-old man on 18F-FDG PET/CT. Lytic bone destruction and the formation of a slightly low-density soft tissue mass extending to adjacent muscles with intense and circular FDG uptake were found on 18F-FDG PET/CT. Postoperative pathology confirmed the diagnosis of myoepithelial carcinoma.

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18F-FDG PET/CT Imaging of Myoepithelial Carcinoma in the Left Femur

Huang,

Xie,

Huang

2024

Clin Nucl Med

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Soft-tissue tumor of myoepithelial origin in leg with secondary bone changes: A rare case report

Mer,

Parikh

2024

IJMSR

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Myoepithelial tumors in skin and soft tissue are uncommon, but have been increasingly characterized over the past decades. They equally affect men and women of all age groups. Lesions are more frequent in extremities and limb girdles. Due to presence of varied architectural and cytological features both within a lesion and between different tumors, immunohistochemistry may be required to diagnose these tumors. We report a rare case of myoepithelial tumor of soft tissue of lower extremity with secondary bone changes on radiographs, as well as magnetic resonance imaging and histopathological correlation. The tumor was initially noticed as a painless, deep soft-tissue mass in the left lower limb; thereafter, the patient started complaining about chronic left lower limb radicular pain. A core needle biopsy was then performed, which discloses nests of ovoid to plasmacytoid cells having monomorphic round nuclei, inconspicuous nucleoli, and clear cytoplasm. Immunohistochemically, the tumor cells were positive for AE1, P40, CK 5/6, and vimentin markers.

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Histological and imaging features of myoepithelial carcinoma of the bone and soft tissue

Cited by 2 publications

References 14 publications

18F-FDG PET/CT Imaging of Myoepithelial Carcinoma in the Left Femur

18F-FDG PET/CT Imaging of Myoepithelial Carcinoma in the Left Femur

Soft-tissue tumor of myoepithelial origin in leg with secondary bone changes: A rare case report

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