Histological Architecture of Gastric Epithelial Neoplasias That Showed Absent Microsurface Patterns, Visualized by Magnifying Endoscopy with Narrow-Band Imaging

Abstract

In recent years, magnifying endoscopy with narrow-band imaging (M-NBI) has permitted the diagnosis of small, flat early gastric cancers, which are difficult to diagnose using conventional white-light endoscopy. 1 In addition, the results of numerous exploratory studies examining the relationship between magnifying endoscopy findings and histological findings have been reported. 2-9 However, the viewing conditions in these investigations, such as the degree of magnification obtained by magnifying endoscopy, have not been uniform, and no studies have reported on a one-to-one correspondence between the site visualized by magnifying endoscopy and the histopathological findings. Uchita et al. reported that the diagnostic accuracy of magnifying endoscopy differs according to the viewing conditions, 10 and that it is ideal to establish uniform viewing conditions at maximum magnification. Major advances in endoscopic diagnosis have been achieved because the morphological features have been confirmed histologically. With magnifying endoscopy, however, the region observed is more minute, and a one-to-one correspondence is therefore required when examining the histological findings for the observed sites. Consequently, Yao et al. reported that in order to match resected gastric epithelial tumor specimens to

Magnifying Endoscopy with Narrow-Band Imaging for Duodenal Neuroendocrine Tumors

“…ME-NBI is a useful diagnostic modality with a maximal resolution power of 6.4 µm for visualizing real-time microscopic images of the mucosal surface [14,15]. The clinical utility of ME-NBI has been investigated mainly in relation to GI epithelial neoplasms [7,16]; however, reports on the use of ME-NBI in GI SELs are rare [17].…”