Histological Classification of Salivary Gland Tumours

Seifert, G.

doi:10.1007/978-3-642-84506-2_2

Cited by 180 publications

(205 citation statements)

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“…Histologically, the present case showed the features reported in the literature [4,7,8], differing in terms of the presence of intense nuclear and cellular pleomorphism, numerous mitoses, some of them atypical, nuclear hyperchromatism, and numerous prominent nucleoli. Some of these features have also been observed in a case of PC located in the tongue [9].…”

Section: Discussionsupporting

confidence: 61%

Papillary cystadenocarcinoma: Report of a case of high-grade histopathologic malignancy

Cavalcante

Miguel

Carvalho³

et al. 2007

Auris Nasus Larynx

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Papillary cystadenocarcinoma is an extremely rare malignant tumor of the salivary gland which is cytologically considered to be of lowgrade malignancy, showing an indolent biological behavior. Histologically, the tumor is characterized by cysts and papillary endocystic projections. This tumor most commonly arises in the major salivary glands, mainly the parotid gland. We report here a case of papillary cystadenocarcinoma originating from the minor salivary gland, which showed marked growth over a short period of time. Histologically, the tumor was characterized by intense cellular and nuclear pleomorphism and numerous mitotic figures. These findings indicate a tumor of highgrade malignancy. #

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Section: Discussionsupporting

confidence: 61%

Papillary cystadenocarcinoma: Report of a case of high-grade histopathologic malignancy

Cavalcante

Miguel

Carvalho³

et al. 2007

Auris Nasus Larynx

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“…3) shows a tumor very similar to CATMSG. Interestingly, Figure 55 of the 2nd edition of the WHO classification of salivary gland neoplasms issued in 1991 [17] illustrates, under the heading of PLGA, a tumor quite similar to those in our paper, which perhaps represents another example of CATMSG. Two other possible candidates for CATMSG were published under different names, and both carcinomas metastasized to the cervical lymph nodes.…”

Section: Differential Diagnosismentioning

confidence: 94%

Cribriform Adenocarcinoma of the Tongue and Minor Salivary Glands: A Review

Michal

Kacerovská

Kazakov

2013

Head and Neck Pathol

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Cribriform adenocarcinoma of the tongue and minor salivary glands (CATMSG) is a tumor occurring mostly, but not exclusively, in the base of the tongue. Other locations are minor salivary glands of the oral cavity. Histopathologically, CATMSG resembles papillary carcinoma of the thyroid gland. It usually reveals a solid growth devoid of colloid, and eosinophilic material present in follicular areas is rather pale in contrast to metastatic foci seen in papillary thyroid carcinoma that shows typical deeply eosinophilic colloid with ''moth-eaten peripheries'' and cystic configuration. In addition, giant multinucleated cells are not observed in CATMSG and psammoma bodies are found only exceptionally. Unlike papillary thyroid carcinoma, CATMSG is composed of hybrid secretorymyoepithelial cells. Most importantly, CATMSG is consistently negative with both thyroglobulin and TTF-1. CATMSG is a distinct tumor entity that also differs from polymorphous low-grade adenocarcinoma by location, cytology, histological architecture, and behavior, with frequent metastases at the time of presentation. Paradoxically, early metastatic disease seen in most cases of CATMSG is associated with an indolent behavior. It makes CATMSG a unique neoplasm among all low-grade salivary gland tumors.

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“…Large cell carcinomas also appear to include examples of poorly differentiated squamous cell carcinoma, high-grade mucoepidermoid carcinoma or undifferentiated carcinomas NOS, [35,36]. Some of this confusion can be traced back to the inclusion of large cell carcinomas and small cell carcinomas as part of the spectrum of ''undifferentiated carcinoma'' [21,35] when rigidly applying the 1991 WHO classification of salivary gland tumors [37].…”

Section: The 2005 World Health Organization (Who)mentioning

confidence: 99%