Histological comparison of demineralized bone matrix and the Ricinus communis polymer on bone regeneration

Abstract

Both materials proved to be biologically compatible, however polyurethane was more slowly resorbed presented considerable better results when compared with demineralized bone matrix.

Guided bone regeneration with polypropylene barrier in rabbit's calvaria: A preliminary experimental study

“…In relation to the evaluation periods, there is great variation in the scientific literature, ranging from seven days to several months [ 23 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ]. The cycle of bone remodeling in rabbits is six weeks, different from dogs (12 weeks) and humans (17 weeks).…”

Reconstruction of the Cranial Vault Contour Using Tissue Expander and Castor Oil Prosthesis

“…Regarding the desirable physical–biological properties and optimum handling of biomaterials, the following should be mentioned: (1) biocompatibility, (2) atoxicity, (3) chemical and organic stability, (4) low infection rate, (5) allowing bone growth or neoformation, (6) having natural resistance which allows adjacent reconstructions of the sinus cavities in the craniomaxillofacial segment, (7) low cost, (8) ease of handling,1234 and (9) viability for prototyping, according to the authors.…”

“…Biopolymers are currently seen as an evolution in the area of bone tissue reconstruction, among which polyurethane derived from castor oil56 stands out.…”

Aplicação de resina poliuretânica derivada do óleo de mamona em formas farmacêuticas gastrorretentivas de liberação controlada

“…Castor oil ( Figure 2), a low-cost and widely available renewable raw material, is unique amongst other vegetable oils due to its high content (around 90%) of ricinoleic acid, a bi-functional fatty acid which possesses secondary hydroxyl functionality, enabling castor oil use as a starting material in the synthesis of PUs . Despite the great interest of castor oil-based PUs as biomaterials in tissue engineering (DONG, LI, ZOU, 2009;DU et al, 2014;LAUREANO FILHO et al, 2007;LEITE, RAMALHO, 2008;NACER et al, 2012;PEREIRA-JUNIOR et al, 2007;SAHAN et al, 2017), only 6 articles and 1 patent describing the use of castor oil-based PU as drug delivery systems were found. Rafienia and coworkers (2006) developed theophylline-loaded polyurethane microspheres, using castor oil as polyol, 4,4'-methylenediphenyl isocyanate (MDI) as isocyanate and ethylene diamine as chain extender.…”