Histological Comparison of Postoperative Wound Care Regimens for Laser Resurfacing in a Porcine Model

Abstract

Postoperative treatments after laser resurfacing vary in their ability to influence the quality of healing.

Use of a novel erbium laser in a Yucatan minipig: A study of residual thermal damage, ablation, and wound healing as a function of pulse duration†

“…However, in this study, all wound sites showed equally sparse in¯ammation (the CO 2 sites showed slightly more). We suggest that the occlusive dressings were responsible for this ®nding; this is supported by other studies where occlusive dressings reduced postoperative in¯ammation [22,23].…”

Re-epithelialization of the skin following CO 2 laser resurfacing

“…The necrotic layer was a barrier for epithelial migration and the cells would migrate beneath this debris from the wound margins. In a recent publication by Davis et al, 11 pigs underwent resurfacing with the Coherent Ultrapulse laser at a setting of 300 mJ, 60 W, density 5 for two passes. The pass sites were wiped between passes with sterile gauze and saline.…”

A comparison of wound healing between a skin protectant ointment and a medical device topical emulsion after laser resurfacing of the perioral area

“…Similar studies have reported infection rates after facial laser resurfacing as 1.13% 32 and 4.3%. 33 As infection may cause scarring, systemic antibiotics and antivirals are routinely used for at least 1 day before and several days after laser resurfacing, 27 as was done in this study. In one head-to-head trial comparing white petrolatum and BTE for the postlaser resurfacing care of wounds, prophylactic antibiotics were not administered.…”