Histomechanische Messungen an menschlichen Leichentracheen

Hartung, W.; Düweling, A.

doi:10.1159/000192356

Cited by 3 publications

(1 citation statement)

References 8 publications

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“…It is well acknowledged that the human trachea is not round in shape. The percentages of elliptical, C-, triangular and U-shaped tracheas and their dependance on sex and age have been well studied [19,30,31]. In addition, the shape of the trachea changes from the larynx towards the bifurcation.…”

Section: Discussionmentioning

confidence: 99%

Theoretical and experimental basis for the development of a dynamic airway stent

Freitag¹,

Eicker²,

Linz³

et al. 1994

Eur Respir J

107

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Three major problems are currently associated with airway stents: mucostasis, formation of granulation tissue, and migration. We wanted to determine whether these problems could be solved by a different stent design. Based on theoretical considerations of an idealized trachea, we developed a dynamic bifurcation stent made of silicone which incorporates horseshoe-shaped steel struts. A flexible posterior membrane enables dynamic compression during cough, whilst the clasps maintain the airway lumen in the face of external compression. The design of the stent cast was based upon computed tomographic (CT)-scan studies of the central airways. Its complex shape provides a smoother distribution of pressure on the mucosa; thereby, lowering the stimulus for granulation formation. The bronchial limbs saddle on the carina, preventing displacement. The mechanical behaviours of the new stent and two commercially available stents were compared in an ex-vivo model, utilizing freshly excised tracheae and new visualization techniques. Dynamic (artificial coughs) and static loads (simulating tumour compression or pleural pressures) were applied on excised human tracheae with different stents. Our dynamic stent preserved effective compression of the posterior membrane in response to cough, and also provided lumen stability against extrinsic compression. In comparison, the two commercially available stents did not provide both functions equally well. In conclusion, our newly designed dynamic bifurcation stent shows characteristics which should prove useful in avoiding problems currently associated with airway stents.

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Section: Discussionmentioning

confidence: 99%

Theoretical and experimental basis for the development of a dynamic airway stent

Freitag¹,

Eicker²,

Linz³

et al. 1994

Eur Respir J

107

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“Saber-Sheath” Trachea: A Clinical and Functional Study of Marked Coronal Narrowing of the Intrathoracic Trachea

Greene¹,

Lechner²

1975

Radiology

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Data are presented from thirteen patients with marked coronal narrowing of the intrathoracic trachea associated with widening of the corresponding sagittal diameter. The term "saber-sheath" trachea describes this deformity which can simulate a mediastinal mass. The absence of mediastinal masses and the presence of obstructive pulmonary abnormalities in each patient, either as a clinical diagnosis (11 of 13), functional abnormality (10 of 11) or both (8 of 11), suggest that the "saber-sheath" trachea may be a useful sign of chronic obstructive pulmonary disease.

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Large Airway Size, Lung Size, and Maximal Expiratory Flow in Healthy Nonsmokers^1,²

et al. 1986

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It has been postulated that airway size and lung size may be dissociated because of developmental differences between the tracheobronchial tree and the pulmonary parenchyma (dysanapsis). To test this hypothesis, we compared measurements of airway size (diameters, cross-sectional area, length and volume of the trachea, diameter and cross-sectional area of the mainstem bronchi) and lung size (total lung capacity, thoracic diameters, lung length), as determined from plain chest radiographs in 79 male and 86 female healthy nonsmokers. In both groups of subjects, the correlation between indexes of airway size and lung size was low. Airway size was not significantly different between men and women, when standardized for lung size. Tracheal diameter and length tended to increase with age. To assess the value of airway size measurements in the prediction of maximal expiratory flow, we compared tracheal and bronchial size with FVC, FEV 0.5, FEV1, and mean forced expiratory flow during the middle half of VC. The correlation between airway size and spirometric indexes was very low. Multiple regression analysis showed that the use of airway size variables in addition to the age and height variables did not substantially improve the prediction of maximal expiratory flow. Our results are consistent with the dysanapsis hypothesis, but they suggest that the introduction of radiologic estimates of large airway size in the prediction equations relating maximal expiratory flow to age and height is not justified, at least in the general population.

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Histomechanische Messungen an menschlichen Leichentracheen

Cited by 3 publications

References 8 publications

Theoretical and experimental basis for the development of a dynamic airway stent

Theoretical and experimental basis for the development of a dynamic airway stent

“Saber-Sheath” Trachea: A Clinical and Functional Study of Marked Coronal Narrowing of the Intrathoracic Trachea

Large Airway Size, Lung Size, and Maximal Expiratory Flow in Healthy Nonsmokers^1,²

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Histomechanische Messungen an menschlichen Leichentracheen

Cited by 3 publications

References 8 publications

Theoretical and experimental basis for the development of a dynamic airway stent

Theoretical and experimental basis for the development of a dynamic airway stent

“Saber-Sheath” Trachea: A Clinical and Functional Study of Marked Coronal Narrowing of the Intrathoracic Trachea

Large Airway Size, Lung Size, and Maximal Expiratory Flow in Healthy Nonsmokers1,2

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Large Airway Size, Lung Size, and Maximal Expiratory Flow in Healthy Nonsmokers^1,²