Histomorphometric Analysis of Biological Responses Following the Use of Pure Hydroxyapatite and Hydroxyapatite With Collagen: A Study in Dorsal Subcutaneous Tissue of Rats / Análise Histomorfométrica Das Respostas Biológicas Após O Uso De Hidroxiapatita Pura E Hidroxiapatita Com Colágeno: Um Estudo No Tecido Subcutâneo Dorsal De Ratos
Abstract:The aim of this study was to evaluate the biological responses resulting from the implantation of two types of experimental hydroxyapatite-Pure Ha (HaP) and Ha with collagen (HaCol) and compare them with a third type HaAlobone (commercial)on dorsal subcutaneous tissue of female rats. Methods: Forty-five animals were used (15 in each group), which were sacrificed 7, 15, and 30 days after operation. The specimens were fixed, stained with hematoxylin and eosin, and then evaluated for inflammatory reactions with a… Show more
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