Histomorphometric Analysis of Zirconia/Alumina Composite and CP Titanium Treaded Implants in Rabbit Tibia

Kam, Min Hee; Han, Jung Suk; Yang, Jihoon; Lee, Jai Bong; Kim, Dae Joon; Lee, Wonjun

doi:10.4028/www.scientific.net/kem.309-311.437

Cited by 2 publications

(1 citation statement)

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“…According to Kangasniemi et al, the interfacial shear strength is related to the friction between the bone and implant, which is dependent on the roughness and the contact area at the surface (20). Kam et al conducted a comparative study on the surface roughness (Ra) of implants and showed that the ceramic material presented adequate osseointegration for dental implants (21).…”

Section: Discussionmentioning

confidence: 99%

Bone Response to Porous Alumina Implants Coated with Bioactive Materials, Observed Using Different Characterization Techniques

Camilo

Silveira

Faeda

et al. 2017

Journal of Applied Biomaterials & Functional Materials

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Background Implants or implantable devices should integrate into the host tissue faster than fibrous capsule formation, in which the design of the interface is one of the biggest challenges. Generally, bioactive materials are not viable for load-bearing applications, so inert biomaterials are proposed. However, the surface must be modified through techniques such as coating with bioactive materials, roughness and sized pores. The aim of this research was to validate an approach for the evaluation of the tissue growth on implants of porous alumina coated with bioactive materials. Methods Porous alumina implants were coated with 45S5 Bioglass® (BG) and hydroxyapatite (HA) and implanted in rat tibiae for a period of 28 days. Ex vivo resections were performed to analyze osseointegration, along with histological analysis, Scanning Electron Microscopy with Energy Dispersive X-Ray spectroscopy (SEM-EDX) line scanning, radiography and biomechanical testing. Results Given that the process of implant integration needs with the bone tissue to be accelerated, it was then seen that BG acted to start the rapid integration, and HA acted to sustaining the process. Conclusions Inert materials coated with bioglass and HA present a potential for application as bone substitutes, preferably with pores of diameters between 100 μm and 400 μm and, restrict for smaller than 100 μm, because it prevents pores without organized tissue formation or vacant. Designed as functional gradient material, stand out for applications in bone tissue under load, where, being the porous surface responsible for the osseointegration and the inner material to bear and to transmit the loads.

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Section: Discussionmentioning

confidence: 99%