Abstract:Epigenetic marks such as histone acetylation and methylation play important roles in the biology and virulence of malaria parasites. Here I report that histone lactylation is also found in these parasites, and speculate on its potential functions. Lactylation is a new epigenetic modification, discovered only in 2019 in human cells. This nascent field has since focussed largely on human biology, but lactyl epigenetic marks could be particularly important in malaria parasites, which are exposed to high and fl… Show more
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