1994
DOI: 10.1002/lary.5541040505
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Histopathologic changes in the aging human cricoarytenoid joint

Abstract: Detrimental effects of the natural aging process on the human cricoarytenoid joint have been hypothesized as a possible etiology for the voice changes seen in the aging population. Cellular events occurring at the histologic level, such as cricoarytenoid joint erosion or arthritis may lead to alterations in laryngeal structure which ultimately affect its function and performance. Seven normal human larynges of varying ages ranging from 29 to 69 years of age were examined histopathologically for changes in the … Show more

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Cited by 39 publications
(27 citation statements)
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“…9,16,17 Other authors considered that cricoarytenoid articulation changes do not have an important role in vocal senescence. 18 Incomplete glottic closing in the elderly is also associated with vocal fold vocal ligament modifications, which are frequent at this age. 19 The phase of vocal fold closing may present alterations associated with aging, which may be related to a situation involving glottic closing insufficiency.…”
Section: Introductionmentioning
confidence: 99%
“…9,16,17 Other authors considered that cricoarytenoid articulation changes do not have an important role in vocal senescence. 18 Incomplete glottic closing in the elderly is also associated with vocal fold vocal ligament modifications, which are frequent at this age. 19 The phase of vocal fold closing may present alterations associated with aging, which may be related to a situation involving glottic closing insufficiency.…”
Section: Introductionmentioning
confidence: 99%
“…7,8 A laringe, com o avançar da idade, também sofre alterações nos aspectos morfológicos, podendo aumentar e exibir fibrose da musculatura envolvida, resultando em redução da mobilidade da estrutura da prega vocal e prejuízo na qualidade vocal. [9][10][11][12] D'haeseleer et al 13 encontraram, na avaliação perceptivo-auditiva da qualidade vocal de mulheres na pós-menopausa, diferenças quanto ao grau de disfonia, principalmente quanto a soprosidade e tensão vocal, comparadas às mulheres na pré-menopausa. Na análise acústica vocal computadorizada, também foram encontradas diferenças estatisticamente significantes nesses dois grupos quanto a faixa de frequência e parâmetros acústicos (frequência fundamental, variação da frequência fundamental, índices de alteração de tremor vocal).…”
Section: Discussionunclassified
“…7,8 Histopathologic studies demonstrated that the stage of the calcification and ossification is widely affected by age. 9 The order of ossification is affected by the distribution of the mechanical forces applied to the laryngeal cartilages. 8 Ossification begins first in the superior border of the lamina in the cricoid cartilage followed by the apex, body, and muscular process of the arytenoid cartilage, with the exception of the vocal process.…”
Section: Discussionmentioning
confidence: 99%