Histopathological Alterations Induced by He–Ne Laser in the Salivary Glands of the Posthatched Chicken

Low-level (gallium-aluminum-arsenide) laser irradiation of Par-C10 cells and acinar cells of rat parotid gland

“…Furthermore, anti-apoptosis proteins were detected after laser irradiation. The results of this study suggest that high-power output irradiation of cells using the Ga-Al-As diode laser does not cause the kind of severe degenerative change shown by Samar et al and Plavnik et al who used He-Ne laser irradiation [9,10], and it would be associated with apoptosis-inhibiting proteins such as HSP25 and bcl-2.…”

“…Samar et al and Plavnik et al reported degenerative and necrotic changes using He-Ne laser irradiation [9,10], while Takeda showed frequent mitotic findings in granular duct cells following gallium-arsenide (Ga-As) low-level laser irradiation at 24 h, suggesting a mitogenic effect with low-level laser irradiation [13]. In the present study, we found that the number of Par-C10 cells in the irradiated groups was higher than that in the non-irradiated group.…”

“…A few studies have also investigated the influence of low-level laser irradiation on salivary gland cells [9][10][11][12][13]. Although these earlier reports demonstrated 13 morphological changes, the influence of low-level laser irradiation on salivary gland acinar cells remains to be fully clarified.…”

“…on low-level laser irradiation of mouse skin to investigate wound healing, many researchers have investigated the influence of laser irradiation on wound healing [1][2][3][4][5], improvement of microcirculation [6], nerve activation [7], treatment of chronic pain and anti-inflammation [8]. The influence of low-level laser irradiation on activation of salivary gland cells has been also investigated [9][10][11][12][13]. Previous investigations showed degenerative and inflammatory changes after helium/neon (He-Ne) low-level laser 4 irradiation, histopathologically [9,10].…”

“…The influence of low-level laser irradiation on activation of salivary gland cells has been also investigated [9][10][11][12][13]. Previous investigations showed degenerative and inflammatory changes after helium/neon (He-Ne) low-level laser 4 irradiation, histopathologically [9,10]. On the other hand, another study found no detectable degenerative changes in rat submandibular gland cells after gallium-arsenide (Ga-As) low-level laser irradiation [13].…”