Histopathological and histochemical studies on atrophic rhinitis

Barbary, Abd El-Salam El; Yassin, Adly; Fouad, H M A; Shennawy, Magid El

doi:10.1017/s0022215100156506

Cited by 28 publications

(12 citation statements)

References 15 publications

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“…The observed abnormalities agreed with the previously reported histopathological [10,11] and scanning electron microscopic features [2,12], and included: (1) marked loss of cilia together with the superficial epi thelial layers; (2) a decrease in the number and activity of goblet cells and seromucinous glands; (3) obliteration of arterioles and cap illaries; (4) excessive collagenosis of the con nective tissue stroma, and (5) absence of his tiocytes, mast cells and plasma cells. Lym phocytes were scarce.…”

Section: Discussionsupporting

confidence: 93%

“…The histopathology of primary atrophic rhinitis has been reported by Fabricant [9], Taylor and Young [10], and El-Barbary et al [11], However, despite the obscure nature of the disease, few papers [2,12] have reviewed some of its ultrastructural features with the scanning electron microscopy. In this work transmission electron microscopy was used to study and analyze the ultrastructural fea tures of atrophic rhinitis, and to evaluate the results of partial nostril closure.…”

Section: Introductionmentioning

confidence: 99%

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Ultrastructural Observations on Primary Atrophic Rhinitis

Elwany

1988

ORL

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Ultrastructural Observations on Primary Atrophic Rhinitis

Elwany

1988

ORL

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“…Oestrogen deficiency is implicated as a causative factor by some authors. 1,33 The incidence of the disease in pubertal girls, the aggravation of symptoms during menstruation and pregnancy, and the improvement of symptoms in some cases with oestrogen therapy support this theory.…”

Section: Primary Atrophic Rhinitismentioning

confidence: 95%

The aetiology and management of atrophic rhinitis

Dutt

Kameswaran

2005

J. Laryngol. Otol.

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Atrophic rhinitis is a chronic, debilitating and recalcitrant disease of the nasal cavities that is prevalent in several parts of the world. It has unique epidemiological features and clinical characteristics. Clinicians and researchers for decades have tried to postulate theories for the aetiology of the primary form of the disease. Management of the disease has seen several medical therapeutic regimens including alternative forms of medicine. Surgical options for the condition are also not completely satisfactory with a number of failures and recurrences. The authors provide here a comprehensive review of the existing literature as regards the aetiology and management of this refractory condition.

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“…Until now it remains unexplained as to what are the aetiological factors and an effective modality of treatment for this distressing disease. 1 Atrophic rhinitis is a chronic nasal disease characterized by progressive atrophy of the nasal mucosa and underlying bone of the turbinates and the presence of viscid secretions which rapidly dries and forms crusts which emits a characteristic foul odour sometimes called oazena (a stench).…”

Section: Introductionmentioning

confidence: 99%

Descriptive study of endoscope assisted creation of neoturbinate by antral mucosal inversion in atrophic rhinitis

Kedarnath

Mushtaq

2017

Int J Otorhinolaryngol Head Neck Surg

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Background: As the exact etiology is not known, treatment is directed towards symptomatic relief. Medical treatment leads only to temporary remission of symptoms. Over the years, surgeons have attempted various techniques for long term relief of symptoms. Most of the techniques have been directed to the narrowing of the nasal cavity. Methods: All the cases diagnosed as primary atrophic rhinitis and who were willing to undergo this surgery were taken for the study. The cases diagnosed as primary atrophic rhinitis were subjected to detailed history and examination. Clinically following conditions were ruled out – tuberculosis, syphilis, rhinoscleroma, leprosy. A routine haemogram (Hb%, TC, DC, BT, CT), urine examination (albumin, sugar, microscopy), ESR serum VDRL was done for the patients. Results: We were successful in creating a neoturbinate in 12 patients in our study. Of these, majority of the patients (6 patients) had their duration of symptoms between 2-4 years, the outcome in them are excellent in 4 patients, good in 2 patients. Conclusions: The results are encouraging with reduced crusting, healthier mucosa and some patients even regaining their sense of smell. All these above, with no nasal obstruction or pinched nostrils as may occur in young’s closure. But the effort involved is more in this surgical procedure.

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Histopathological and histochemical studies on atrophic rhinitis

Cited by 28 publications

References 15 publications

Ultrastructural Observations on Primary Atrophic Rhinitis

Ultrastructural Observations on Primary Atrophic Rhinitis

The aetiology and management of atrophic rhinitis

Descriptive study of endoscope assisted creation of neoturbinate by antral mucosal inversion in atrophic rhinitis

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