Histopathological and Parasitological Study of Blood-Sucking Haemonchus contortus Infection in Sheep

Saminathan, Mani

doi:10.14737/journal.aavs/2015/3.2.99.108

Cited by 13 publications

(23 citation statements)

References 15 publications

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“…In the current study, the presence of blood tinged, dark red fluid contents in the abomasa of infected animals indicating abomasal mucosal hemorrhages due the sucking habits of H. contortus parasite. These findings were fully agreed with the findings reported earlier by Pérez et al [77], Tehrani et al [78] and Saminathan et al [79].…”

Section: Discussionsupporting

confidence: 94%

Therapeutic Effect of Balanites Aegyptiaca Fruit’s Ethanol Extract in Egyptian Baladi Goats Experimentally Infected with Haemonchus Contortus: Blood Serum Biochemical, Oxidative Stress Markers and Pathological Studies

et al. 2020

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the native breed of goats that is located in the Nile Delta and along the Nile Valley is known as Baladi goats. Amongst other breeds of goats, the Baladi goats have a great economic value [1] and play an essential role in the economy of small, marginal farmers and landless labourers in Egypt [2]. T HE THERAPEUTIC effect of Balanites aegyptiaca fruit's ethanolic extract (BAF-EE) in goats experimentally infected with Haemonchus contortus (H. contortus) was evaluated. Serum biochemical parameters, tissue oxidative stress status and pathological changes were investigated. Twelve goats were divided into 4 equal groups, G1 (infected-untreated), G2 (infected-BAF-EE treated), G3 (infected-albendazole treated) and G4 (uninfected-BAF-EE treated). Infection was conducted at 0-time, whereas treatment with BAF-EE and albendazole was given in the 5 th week post infection (PI). Blood samples were drawn on 0-time, 3 rd week PI and then biweekly till the 9 th week for serum biochemical analyses. At the end of experiment, all animals were slaughtered to estimate oxidative stress markers and histopathological alterations in the abomasal and hepatic tissues. Serum biochemistry of infected animals showed significant depression of total serum proteins, albumin, albumin/ globulin ratio, total antioxidant capacity and calcium levels. The activity of AST, ALT and γGT and the cholesterol, urea and creatinine levels were significantly elevated in the serum of infected animals. Glutathione peroxidase values decreased significantly in tissue homogenate of G1 and G3 goats than those in G2 and G4 goats. Malondialdehyde followed a reverse course. Abomasa of infected animals in G1 revealed inflammation, necrosis, petechial hemorrhages and cellular infiltration. Liver showed bile duct hyperplasia, degeneration of hepatocytes and cell infiltration. Intensity of alterations were lower in infected-treated animals. In conclusion, BAF-EE has hepatoprotective effect and can improve serum biochemical alterations and oxidative stress status in goats infected with H. contortus, justifying its use as a safe natural anthelmintic agent.

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Section: Discussionsupporting

confidence: 94%

Therapeutic Effect of Balanites Aegyptiaca Fruit’s Ethanol Extract in Egyptian Baladi Goats Experimentally Infected with Haemonchus Contortus: Blood Serum Biochemical, Oxidative Stress Markers and Pathological Studies

et al. 2020

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“…(Ahmad et al 2012). Haemonchus contortus adalah cacing nematoda gastrointestinal penghisap darah (Mini 2012;Gidey 2017) paling patogenik yang ditemukan di dalam abomasum ruminansia kecil terutama pada kambing dan domba (Pathak et al 2013), sementara pada sapi umumnya ditemukan H. placei (Saminathan et al 2015;Sakti 2018) Parasit patogenik ini memiliki luas penyebaran dan tingkat infeksi mencapai 80% (Lastuti et al 2006). Suteky & Dwatmadji (2010) menyatakan bahwa infestasi H. contortus pada kambing dapat mengakibatkan kematian hingga mencapai 66,7%.…”

Section: Pendahuluanunclassified

“…Cairan yang ditemukan di bagian abdomen beberapa diantaranya bercampur dengan darah karena infestasi H. contortus dewasa dalam jumlah yang sangat besar (Javanbakht et al 2014;Rahman et al 2017;Chikweto et al 2018). Saminathan et al (2015) melaporkan bahwa pada rongga dada ditemukan cairan kurang lebih 500 ml, sedangkan pada rongga abdomen ditemukan cairan kurang lebih 500 -750 ml (Gambar 5). Studi Jesse et al (2019) juga menunjukkan bahwa kambing yang mengalami infeksi H. contortus kronis mengalami hidrotoraks yang ditandai oleh 400 ml cairan yang bercampur dengan darah saat dilakukan pemeriksaan post mortem.…”

Section: Patologi Anatomiunclassified

Pathological Aspects of Haemonchosis in Goats and Sheeps

Ahmad

Tiffarent

2020

WARTAZOA

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<p class="awabstrak2">Haemonchosis in sheep and goats has a high prevalence rate in several regions in Indonesia and causes economic losses. The purpose of this paper is to explain the clinical symptoms and pathological aspects of <em>Haemonchus contortus</em> infection so that knowledge is expected to help in controlling haemonchosis. Clinical symptoms of haemonchosis is characterised by decreased production, cachexia, and severe anaemia due to worms that sucking blood from the abomasal mucosa. In chronic infections the symptoms shows general oedema. Gross pathological findings are pale mucosa and carcass, hydrothorax, ascites, and haemorrhagic abomasum. Whereas histopathological features shows desquamation of villous abomasum, extensive hemorrhage of abomasal mucosa-submucosa, infiltration of large numbers of eosinophil and mononuclear cells, and cells undergoing degeneration and necrosis of internal organs. In general, the above exposure will show that haemonchosis usually associated with anaemia, cachexia, oedema, haemorrhage, infiltration of eosinophil and mononuclear cells in the abomasal mucosa.</p>

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“…The most common findings were peritoneal, thoracic and pericardial effusions, visceral pallor, subcutaneous oedema and serous atrophy of fat. Histological lesions included centrilobular hepatic necrosis, hepatic atrophy, lymphoplasmacytic inflammation of the mucosa of the third gastric compartment (C3), extramedullary hematopoiesis in both the liver and spleen (Edward et al, 2016;Saminathan et al, 2015) revealed severe congestion of abomasum with pin point petechial haemorrhages in H. contortus infection in goats. On histopathological examination revealed haemorrhages, oedema, desquamation and eosinophilic infiltration in the abomasal villi.…”

Section: Histopathological Study Of Parasite Infested Organmentioning

confidence: 99%

Pathological Studies of Mecistocirrus digitatus Infection in Naturally Infested Mithun and Phere (Cross Bred of Mithun)

Chamuah

Amenti

Borkotoky

2020

IJAR

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In histopathological study, Lung was emphysematous, showed pronounced interstitial pneumonia followed by severe thickening of alveolar septa and bronchial wall, haemorrhages with connective tissue proliferation and infiltration of leucocytes around the bronchial wall. Bulla formation was also evident in some places. Liver showed mild haemorrhages of hepatocytes and congestion in sinusoidal space. In abomasum, adult parasites were embedded in mucousa and sectioning of adult parasites were seen with full of eggs. In large intestine, there was necrosis and degeneration of colonic villi and lost of normal architecture. There was also evidence of hyperactivity of acinar cells, fibrous tissue proliferation with polymorphonuclear cell infiltration. An apical tip shows degenerative changes, adhesion with mild fibrous tissue proliferation. In small intestine, there was congestion, oedema with thickening of sub mucousa as well as erosion of intestinal villi in certain areas, adhesion and fibrous tissue proliferation. In spleen, there was depletion of spleenic venule, congestion of spleenic pulp, haemorrhages surrounding the spleenic venule.

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Histopathological and Parasitological Study of Blood-Sucking Haemonchus contortus Infection in Sheep

Cited by 13 publications

References 15 publications

Therapeutic Effect of Balanites Aegyptiaca Fruit’s Ethanol Extract in Egyptian Baladi Goats Experimentally Infected with Haemonchus Contortus: Blood Serum Biochemical, Oxidative Stress Markers and Pathological Studies

Therapeutic Effect of Balanites Aegyptiaca Fruit’s Ethanol Extract in Egyptian Baladi Goats Experimentally Infected with Haemonchus Contortus: Blood Serum Biochemical, Oxidative Stress Markers and Pathological Studies

Pathological Aspects of Haemonchosis in Goats and Sheeps

Pathological Studies of Mecistocirrus digitatus Infection in Naturally Infested Mithun and Phere (Cross Bred of Mithun)

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