1993
DOI: 10.1111/j.1464-410x.1993.tb16172.x
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Histopathological Changes in Kock Pouch

Abstract: To investigate whether tumour recurrence or histological changes occur in the Kock pouch, periodic endoscopy with biopsy of the pouch was performed in 15 patients 6 to 66 months after radical cystectomy and urinary diversion for invasive bladder cancer. Endoscopy was undertaken 1 to 4 times in each patient (a total of 37 times in all patients). During endoscopy, random biopsies were taken from the pouch wall, and from the afferent and the efferent nipples. The histological changes were graded as: (1) villous a… Show more

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Cited by 15 publications
(9 citation statements)
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“…As to the continent reservoir, most data were derived from Koch pouches [20, 21, 22]that differ in many aspects from the orthotopic neobladders considered here. There are several reports concerning this latter type of reservoir, but the results are not completely consistent.…”
Section: Discussionmentioning
confidence: 99%
“…As to the continent reservoir, most data were derived from Koch pouches [20, 21, 22]that differ in many aspects from the orthotopic neobladders considered here. There are several reports concerning this latter type of reservoir, but the results are not completely consistent.…”
Section: Discussionmentioning
confidence: 99%
“…These morphological modifications were very similar to the alterations registered in ileal urinary reservoirs, although complete flattening of the mucosa is rare in the latter. 5,6,11,12 Interestingly, although the absolute number of the goblet cells in the ileal mucosa of the voice tube decreased as a consequence of blunting and disappearance of villi and crypts, there was a relative increase over the enterocytic population. This could represent a protective mechanism to the mucosa.…”
Section: Discussionmentioning
confidence: 93%
“…Fourteen patients required a secondary procedure to correct the incontinence of the ileocecal valve (5), redundancy of the ileal conduit (5), and dysphagia secondary to stricture formation at pharyngocolic junction (4). During the revision procedure, a biopsy of the voice tube was performed to assess morphological and proliferative changes, and the voice tube was probed to assess for internal synechiae, strictures, and occlusion.…”
Section: Matherials and Methodsmentioning
confidence: 99%
“…While the former change is probably due to the chronic irritative action of urine and/or infection, the latter aspect may be the result of the increased wall tension sustained by ileum as already observed in the ileal pouch [Chen et al, 1993].…”
Section: Discussionmentioning
confidence: 99%