Histopathological comparison of healing after maxillary sinus augmentation using xenograft mixed with autogenous bone versus allograft mixed with autogenous bone

Abstract

Both composite grafts generate adequate substratum to receive dental implants after healing. Compared with the xenograft composite, allograft composite shows faster turnover and a quicker decrease in biological action after 6 months.

Histological and immunohistochemical comparison of two different allogeneic bone grafting materials for alveolar ridge reconstruction: A prospective randomized trial in humans

“…However, the allogeneic graft material was mixed with autogenous bone in a ratio of 1:1 . This was also the case in a sinus augmentation study of Galindo‐Moreno et al (2018) . Recently, a study on 14 patients calculated 18.65% of new bone when using allogeneic spongious bone blocks (Tutobone) for vertical and horizontal ridge augmentation prior to implant placement .…”

“…This histological picture resembled that of other histological studies in humans on the healing of different allograft materials. [42][43][44][45][46][47] Similar findings could also be obtained in animal studies, although they are not directly comparable with the human situation as any use of human-derived material in animals is classified as xenogeneic. Additionally, the clinical procedures in most animal studies using human bone grafts have been undertaken in long bones or for critical size defects in jaw bones.…”

“…Allogeneic grafts or their remnants could be clearly identified as more basophilic stained bone fragments with empty osteocyte lacunae histologically. This histological picture resembled that of other histological studies in humans on the healing of different allograft materials . Similar findings could also be obtained in animal studies, although they are not directly comparable with the human situation as any use of human‐derived material in animals is classified as xenogeneic.…”

“…This was in contrast to a study using fresh-frozen cortical and cortico-cancellous allogeneic block grafts for augmentation of the anterior maxilla, which found necrotic areas as well as reduced incorporation, remodeling, and increased resorption of these grafts. 49 There are only very few studies comparing histomorphometric data obtained after sinus lift procedures using allogeneic bone substi- 47 Recently, a study on 14 patients calculated 18.65% of new bone when using allogeneic spongious bone blocks (Tutobone) for vertical and horizontal ridge augmentation prior to implant placement. 27 As mentioned above, a direct comparison to our study is not possible since we used those materials for lateral ridge augmentation.…”

Influence of the use of autogenous bone particles to close the access window after maxillary sinus floor augmentation: an experimental study in rabbits

“…For this reason, and because of the less patient morbidity and risk of complications, intraoral autogenous bone harvesting is routinely used [26,27]. Intraoral particulated bone (intramembranous origin) can be obtained from the cortical bone of the lateral window [28] or from neighbor intraoral areas (e.g., from the ramus, or the chin, or retromolar area). The difference in the origin of the autograft should be taken into consideration when interpreting the results of the present preclinical study.…”