Histopathological evaluation of endometrial sampling in different age groups - 1374 cases

Azatçam, Meltem; Altun, Eren; Usta, Akın

doi:10.5222/mmj.2017.026

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…In a study by Azatçam et al, which evaluated 1,374 endometrial biopsies, the most common diagnosis was an endometrial polyp, with a rate of 37.2% (24). In the present study, although the rate of polyps was 16.1%, which was higher than other pathology results, the highest rate was the proliferative-secretory endometrium (56.9%).…”

Section: Discussioncontrasting

confidence: 69%

Histopathological Evaluation of Endometrial Biopsies in Different Age Groups: A Tertiary Care Experience in Turkey

2023

ircmj

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Background: An endometrial biopsy primarily aims to determine endometrial cancer and hyperplasia with atypia at an early stage. Objectives: This study aims to evaluate the indications, histopathological diagnoses, and the number of endometrial biopsies performed in our clinic, according to the age groups of patients, in light of the literature. Methods: A retrospective review was conducted on the file data of 4,965 patients who underwent endometrial biopsy for non-obstetric reasons between 2014-2021. The patients were divided into five groups, according to their age. Pathology diagnoses were classified as benign endometrial pathology, premalignant-malignant pathology, and insufficient for diagnosis. Results: The most common biopsy indication was abnormal uterine bleeding (61.9%), while the most common histopathological result was benign endometrial pathologies (75.3%). Endometrial cancer was also detected in 3% of the patients. The highest diagnosis of benign endometrial pathology among age groups was 96.6% in those below 35. The comparison of age groups in the diagnosis of premalignant-malignant pathology revealed that the highest diagnosis rate was 32.1% in those 65 years and over. Furthermore, the evaluation of the relationship between indications and material adequacy showed that the highest rate of insufficient for diagnosis pathology was in the postmenopausal patient group (34.0%). Moreover, insufficient for diagnosis and endometrial surface epithelium results were highest in patients over 65 (46.7%). Conclusion: Patients aged 55-64 and those over 65 had the highest rate of endometrial cancer and insufficient for diagnosis biopsy results. Therefore, dilation and curettage may be recommended while taking a biopsy from patients in this age group.

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Section: Discussioncontrasting

confidence: 69%

Histopathological Evaluation of Endometrial Biopsies in Different Age Groups: A Tertiary Care Experience in Turkey

2023

ircmj

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“…Endometrial samples can be obtained via methods of dilation curettage, Pipelle biopsy, or hysteroscopy. The most common diagnoses reached based on endometrial samples were reported in the literature as; normal cyclic pattern and EP (2).…”

Section: Introductionmentioning

confidence: 99%

Clinical and histopathological analysis of 1694 cases diagnosed with endometrial polyps based on endometrial sampling

Şahin¹,

Çoban²,

Sezal³

et al. 2019

Ann Med Res

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All the patients presented to gynecology polyclinics with abnormal uterine bleeding either during the reproductive or the peri/ postmenopausal period underwent endometrial sampling to exclude endometrial pathologies. One endometrial pathology frequently encountered in the histopathological examination of these samples is Endometrial Polyp (EP); and it is important that they are recognized as they require a distinct treatment plan and can be associated with endometrial malignancies. Material and Methods: In this study, we investigated the demographic and clinical findings and concomitant malignancies of the cases diagnosed with endometrial polyps based on endometrial biopsy samples at Bezmialem Vakif University over a period of 7 years and compared our results with those in the literature. Results: Our study determined an EP prevalence of 19% and only 11 (0.65%) of the 1694 cases were found to have "adenocarcinomas" within/outside the polyp. Conclusion: Considering that EPs may be associated with malignancies, histopathological examination must absolutely be performed with adequate sampling.

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Histopathological evaluation of endometrial sampling in different age groups - 1374 cases

Cited by 2 publications

References 16 publications

Histopathological Evaluation of Endometrial Biopsies in Different Age Groups: A Tertiary Care Experience in Turkey

Histopathological Evaluation of Endometrial Biopsies in Different Age Groups: A Tertiary Care Experience in Turkey

Clinical and histopathological analysis of 1694 cases diagnosed with endometrial polyps based on endometrial sampling

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