Introduction: (1) The female genital tract is constituted by the ovaries, fallopian tubes, uterus (body/corpus and cervix), vagina, and vulva. Female
genital tract lesions can be benign or malignant. Our study was carried out to nd out the frequency of various histopathological lesions including
neoplasms of female genital tract. Materials and Methods: Our study is retrospective conducted over 2 years period. Data was collected from case
records of patients presenting to Goa Medical College and histopathology reports obtained from Dept of pathology. Data was represented in form
of charts and tables. The analysis of statistical data of variables was done using SPSS software version 22. Signicance was calculated using chi
square test. Value of p <0.05 was considered signicant. Results: Out of total 270 subjects studied, 229 were having benign lesions and 41 had
malignant lesions.The mean age was 49.5 years. Leiomyoma was diagnosed in (40.58%) cases. In abnormalities of endometrium proliferative
endometrium was seen in 37.6%. Chronic cervicitis was seen 78.74% cases. Among the ovarian lesions, 67.74% cases were simple follicular cysts.
Cervical cancer was found in 73.17% cases followed by ovarian malignancies in 19.51 % cases, endometrial carcinoma in 4.87% cases and vulvar
cancer in 2.44% cases. Among the malignant tumors (58.54%) cases were postmenopausal women. Conclusion: Microscopic assessment and
clinico-pathological correlation of lesions is necessary as grossly identiable benign lesion may harbour a focus of malignancy. It aids to
appropriate management in the postoperative period. A concerted effort should be done towards prevention of cancers, by creating awareness
through health education in addition to implementation of screening methods.