Histopathological spectrum of ovarian tumours from a referral hospital in Kashmir valley, Jammu and Kashmir, India

Sheikh, Sheema; Bashir, Humaira; Farooq, Summyia; Beigh, Arshi; Manzoor, Farzana; Reshi, Ruby

doi:10.18203/2320-6012.ijrms20171852

Cited by 12 publications

(18 citation statements)

References 5 publications

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“…Sheikh S et al in her study found maximum cases in 21-40 years of age group similar to that seen in our study [27]. Peak age for benign tumours were seen in 3rd to 4th decade, which is similar to study done by Dhakal R et al and Sawant A et al [28,29].…”

Section: Discussionsupporting

confidence: 91%

Study of frequency and histopathological pattern of soft tissue tumours in tertiary care centre of Gandhinagar, Gujarat

Patel

2019

Trop J Pathol Microbiol

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Background: Ovaries are complex intra-pelvic organs of the female reproductive system. Ovarian cancer accounts for 3% of all cancers in females and is the fifth most common cause of cancer death in women. Early menarche, late menopause, nulliparity and high socioeconomic status are associated with an increased risk for ovarian neoplasms. Histopathological diagnosis remains the mainstay to differentiate neoplastic lesions from non-neoplastic lesions. Aims and Objectives: This study aims to analyze the view of ovarian tumors with respect to clinical presentation, gross and microscopic characteristics and also to study the frequency and histopathological patterns of ovarian tumours. Materials and Methods: This study comprised of 100 cases of ovarian tumours received in the Department of Pathology, GMERS Medical College, Gandhinagar were analysed. Their gross features, microscopic findings were analysed in detail. Ovarian tumours were divided into benign and malignant categories and their further sub typing were done according to WHO Classification. Results: Out of total 100 cases, 76 were benign and 24 were malignant. Out of 100 cases, 62% were between 21-40 years of age followed by 28% were between 41-60 years of age. Most common presenting symptom was pain in abdomen followed by lump in abdomen and heavy menstruation. Out of total 100 cases, 70% were surface epithelial tumours, 24% were germ cell tumours and 6% were sex cord stromal tumours. Conclusion: To conclude we recommend microscopic histopathological examination of every ovarian mass in order to assess the importance of pathological grading and staging and they must be classified correctly so that the patient can be provided with appropriate treatment and prognosis.

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Section: Discussionsupporting

confidence: 91%

Study of frequency and histopathological pattern of soft tissue tumours in tertiary care centre of Gandhinagar, Gujarat

Patel

2019

Trop J Pathol Microbiol

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“…In current study among 84 neoplastic lesions, 74(88%) cases were benign, 3(3.6%) cases were of borderline nature while 7(8.4%) cases were malignant. This is in synchrony with the study of Sheikh et al N Gupta et al [30,31] while contradictory to study by Ahmad Z et al where malignant lesion was comparatively high(40.6%) [32].…”

Section: Discussionsupporting

confidence: 80%

“…However, the germ cell tumor (21.3%) was the second most encountered ovarian tumors in our locality . This report is in contradiction with reports from India by Sheikh et al [30], Lagos by Onyiaorah et al where germ cell tumor was the most common ovarian lesion followed by surface epithelial tumors [33]. Pilli et al reported that ovarian epithelial surface tumors accounted for 70.9% of all ovarian tumors; this is followed by germ cell tumors constituting 21.2%.…”

Section: Discussionmentioning

confidence: 56%

Histopathological Spectrum of Ovarian Lesion in a Tertiary Care Hospital over a Period of Five years

Ahmad¹,

Hassan²,

Khan³

et al. 2019

SJPM

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Introduction: Ovarian lesions are commonly encountered lesions of diverse morphological spectrum that may develop from neonatal period to post-menopause. They are amongst the most frequent cause of hospitalization and surgery in gynaecological practice. Distinguishing non-neoplastic lesion from a neoplastic lesion on the basis of clinical, radiological or gross characteristics alone is a challenge, thus histopathological examination is must as it is also important in guiding therapy. Objectives: This study was undertaken to study the various histopathological patterns of ovarian lesions, their classification and relative distribution of these lesions. Material and Methods: This is a retrospective study of ovarian lesion specimen that was received in the Histopathology section of our department over a period of 5 years from January 2013 to December 2017. Results: A total of 190 cases of ovarian lesions were included in this study with age range from 14 years to 75 years. 106 were non-neoplastic and 84 were neoplastic in nature. Functional cyst including Corpus luteal cyst was the commonest non-neoplastic lesion (26 cases) followed by 21 cases each of endometriotic cyst and simple cyst. Out of 84 neoplastic lesions, 74 were benign, 3 were Borderline and 7 were malignant in nature. Serous cystadenoma was the commonest benign lesion and Serous carcinoma was the most common malignant tumor in our study. Conclusions: Ovarian lesions comprises of wide spectrum of lesions and their presenting clinical, radiological and gross features are very similar. Hence Histopathology forms the mainstay of definitive diagnosis and categorization of these lesions.

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“…Ovary is subjected to monthly endocrine and traumatic insults during normal ovulatory cycles and becomes susceptible to tumorogenesis. 7 The concept of a fallopian tube origin for high grade serous carcinomas arose initially from studies on women with BRCA1/2 germline mutations who were discovered at the time of prophylactic salpingooophorectomy to have areas of marked epithelial atypia in their fallopian tubes. The lesions, called serous tubal intraepithelial carcinoma(STIC), have since been described in association with spontaneous high grade serous carcinoma arising from the fallopian tube.…”

Section: Discussionmentioning

confidence: 99%

Histopathological Spectrum pf Ovarian Neoplasms in a Tertiary Care Hospital

Dutta¹,

Imran²,

Saikia³

et al. 2018

IJCMR

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Introduction:Ovarian cancer accounts for about 3% of all cancers in women and is one of the leading causes of mortality among all cancers of female genital tract. Incidence rate was 10.2/100,000 females in India in 2013. Study aimed to record the histopathological spectrum of ovarian neoplasms over a period of 1 year in a tertiary care hospital. Material and methods:This retrospective study was done for a period of 1 year (. Here we studied 70 cases of ovarian mass specimen received and fixed in 10%formalin. 4-5micrometer thick sections were cut on microtome and stained by H and E stain for Histopathological Examination Results: In this study, 70 cases of ovarian neoplasms were analysed. Out of these, 68 were primary and 02 were metastatic tumours. Amongst the primary ovarian tumours, 52 were benign, 5 were borderline and 11 were malignant. Histopathologically, surface epithelial tumours were the commonest (36), second most common was germ cell tumour (27) followed by sex cord stromal tumours (5). Benign tumours were common in 21-30 years of age, borderline tumours in 61-70 years of age and malignant tumours in 41-50 years age group. Conclusion:Ovary is a common site of neoplasia in the female genital tract and usually presents with a variety of clinicomorphological and histological features. We have observed an increased incidence of malignancy in our set up because patients usually present in advanced stages of disease, and this is an alarmig finding

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Histopathological spectrum of ovarian tumours from a referral hospital in Kashmir valley, Jammu and Kashmir, India

Cited by 12 publications

References 5 publications

Study of frequency and histopathological pattern of soft tissue tumours in tertiary care centre of Gandhinagar, Gujarat

Study of frequency and histopathological pattern of soft tissue tumours in tertiary care centre of Gandhinagar, Gujarat

Histopathological Spectrum of Ovarian Lesion in a Tertiary Care Hospital over a Period of Five years

Histopathological Spectrum pf Ovarian Neoplasms in a Tertiary Care Hospital

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