“…While pursuing this study in the stochastic-model-based approach for histopathology image analysis and classification, we met with certain challenges such as to (i) select the proper kind of model as AR, moving average (MA), ARMA, Markov models (MRF) and also model orders, (ii) select the proper method to estimate the model parameters (iii) select proper neighbourhood, checking complexity in estimation process and accuracy in classification and (v) select classifier, which is also very crucial as classifier output (accuracy of classification) is a feature-specific component. [1] …”